Results 171 to 180 of about 3,484 (305)

A DNA methylation assay (MPap) using self‐collected tampon versus cytology collection swab for endometrial cancer detection

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To evaluate the practicability of self‐collected tampons with the MPap assay for endometrial cancer (EC) detection, by comparing with the results of cervical swabs. Methods A total of 85 women at Tri‐Service General Hospital (TSGH) were included to directly compare the performance of physician‐collected swabs and self‐collected ...
Kuo‐Min Su   +5 more
wiley   +1 more source

A plasmonic and intelligent sweat sensing patch for large‐scale health monitoring

open access: yesInfoMat, EarlyView.
We designed a miniaturized and intelligent sweat sensing patch that collects sweat through a microfluidic module and analyzes it using multimodal laser sensing and artificial intelligence‐assisted diagnosis. This patch enables rapid, large‐scale health monitoring and diagnosis by detecting multiple biomarkers in sweat, offering a noninvasive ...
Yuanchao Liu   +13 more
wiley   +1 more source

Chinese pan‐cancer patient genomic characteristics: A comprehensive analysis based on the National Cancer Center–Clinical Diagnostics Knowledgebase real‐world clinical sequencing cohort

open access: yesInterdisciplinary Medicine, EarlyView.
We assembled National Cancer Center–Clinical Diagnostics Knowledgebase, a clinical genomic knowledgebase of 6935 tumors with matched normal samples, revealing key somatic alterations and actionable variants (70.2% of the cohort). Enrichment of certain different gene mutations was observed between Chinese and American populations, along with a strong ...
Hongrui Li   +10 more
wiley   +1 more source

Decoding temporal miRNA signatures of semen under in vitro exposure for forensic time since deposition estimation using machine learning‐driven modeling

open access: yesInterdisciplinary Medicine, EarlyView.
This study develops a novel miRNA‐based framework for estimating the time since deposition of semen stains, combining small RNA sequencing with machine learning. Time‐dependent miRNA modules were identified using Mfuzz clustering and WGCNA, followed by a multi‐stage feature selection pipeline that reduced 261 candidate miRNAs to a minimal 7‐miRNA panel.
Meiming Cai   +11 more
wiley   +1 more source

Depolarization‐Based Multimodal Optical Imaging of Carious Lesions

open access: yesJournal of Biophotonics, EarlyView.
Occlusal caries is visualized using non‐ionizing imaging techniques, including polarization‐sensitive OCT (PS‐OCT). The image collection captures different stages of lesion development and supports the interpretation of optical signals by comparison with histology.
Julia Grundmann   +7 more
wiley   +1 more source

Genetic and environmental influences on sleep quality, ability to settle, and crying duration in 2‐ and 5‐month‐old infants: A longitudinal twin study

open access: yesJCPP Advances, EarlyView.
This study found that genetic factors largely influence crying duration and settle ability in infancy, while shared environmental factors primarily affect the number of night wakeups. Etiological influences tended to change from 2 to 5 months, reflecting a highly plastic period in infant brain development and in child‐environment interactions. Abstract
Charlotte Viktorsson   +5 more
wiley   +1 more source

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