Results 71 to 80 of about 1,246 (157)

Oral Spermidine Supplementation Preserves Submandibular Gland Function After Radiotherapy: Mechanistic Insights and Use in a Phase II Randomized Clinical Trial

MedComm, Volume 7, Issue 8, August 2026.
Radiotherapy‐induced xerostomia severely impairs quality of life. Integrated multiomics, organoids, murine models, and a randomized Phase II trial identified spermidine as a key radiation‐responsive metabolite. Oral spermidine preserved salivary gland function, maintained acinar cell integrity through Golgi‐mediated posttranslational modifications ...
Yu Min, Kun Gao, Yingtong Liu, Lei Dai, Xingchen Peng   +4 more
wiley   +1 more source

Whole‐transcriptome sequencing analyses identified exosomal circular RNAs in the plasma of pancreatic cancer patients as novel blood‐based biomarkers of disease

VIEW, Volume 7, Issue 4, August 2026.
Pancreatic cancer (PaCa) has a poor prognosis, with low resection rates and high relapse rates, highlighting the urgent need for novel diagnostic biomarkers. Here, we performed whole‐transcriptome sequencing of plasma‐derived exosomes from PaCa patients and identified several differentially expressed circular RNAs (circRNAs).
Xiaomeng He, Yang Di, Lixiang Sun, Zhirong Wu, Mengting Luo, Xin Zhang, Huaqin Sun, Wanli Xu, Wenchuan Wu, Boheng Zhang, Jin Wang   +10 more
wiley   +1 more source

Clinical Implications and Research Progress of Salivary Biomarkers for Endocrine and Metabolic Disorders

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 6561-6575, August 2026.
ABSTRACT Aims Similar to blood, saliva contains a broad range of biomarkers and may offer a non‐invasive, repeatable specimen for endocrine and metabolic assessment. This review aims to synthesise and evaluate recent advances in the clinical translation of salivary biomarkers, while providing a critical assessment of the diagnostic reliability and ...
Chuyan Yu, Jiaying Ni, Qian Dou, Hang Su, Ziyi Zhang, Xiaojing Ma, Qing Dai, Jian Zhou   +7 more
wiley   +1 more source

Awareness and Usage of Water Irrigation Devices Among Implant Patients: A Cross‐Sectional Study

International Journal of Dental Hygiene, Volume 24, Issue 3, Page 481-491, August 2026.
ABSTRACT Background Dental implants are a preferred treatment option for partially or completely edentulous patients. However, they come with challenges, such as peri‐implant diseases requiring effective maintenance, including water irrigation devices (WID).
Amal Jamjoom
wiley   +1 more source

A Comparison of Endodontic Microbiomes Associated With Symptomatic and Asymptomatic Apical Periodontitis by Next‐Generation Sequencing

International Endodontic Journal, Volume 59, Issue 8, Page 1608-1618, August 2026.
ABSTRACT Aim This cross‐sectional study aimed to compare the endodontic microbiome assessed from root canals of teeth associated with either symptomatic or asymptomatic apical periodontitis and analysed by 16S rDNA gene sequencing. Methodology 60 teeth presenting clinical and radiographic signs of symptomatic or asymptomatic apical periodontitis (n ...
David Donnermeyer, Edgar Schäfer, Daniel Hagenfeld, Benjamin Ehmke, Karola Prior, Dag Harmsen, Madgalena Ibing, Sebastian Bürklein, Thomas Gerhard Wolf, Johannes Matern   +9 more
wiley   +1 more source

Transient Hyperattenuating Oral Pseudolesion Mimicking Sialolithiasis Incidentally Detected on Chest Computed Tomography. [PDF]

Am J Case Rep
Tokue H, Tokue A, Tsushima Y.
europepmc   +1 more source

Unraveling Oral Dysbiosis: Microbial Complexity in Common Oral Diseases. [PDF]

Microbiologyopen
Kang Z, Huang H, Lin J, Niu Y, Chen J, Tang J, Hu Z, Liu P, Qu J.   +8 more
europepmc   +1 more source

Giant Asymptomatic Submandibular Sialolith: A Case Report Accompanied by Systematic Review. [PDF]

Clin Pract
Azevedo RG, Toro LF, Ganzaroli VF, Ifanger VJ, de Faria NA, de Rezende RU, da Conceição Francisquini J, Tessarin GWL.   +7 more
europepmc   +1 more source

Giant calculi of the excretory duct of the submandibular salivary gland – case report

Journal of Stomatology (Czasopismo Stomatologiczne), 2012
Marcin Jędrzejewski, Katarzyna Sporniak-Tutak   +1 more
openaire   +1 more source

The Silent Giant: A Case of Giant Submandibular Sialolithiasis with Minimal Symptoms. [PDF]

Curr Health Sci J
Maltese GF, Luppi F, Spampinato MD, DE Giorgio R, Guarino M.   +4 more
europepmc   +1 more source