Results 141 to 150 of about 44,660 (250)

Regulatory T cells in primary sjögren disease: regulatory mechanisms and therapeutic prospects. [PDF]

open access: yesFront Immunol
Chengzhi W   +5 more
europepmc   +1 more source

Exocrine Gland Dysfunction in Parkinson's Disease: Pathophysiology, Clinical Manifestations, and Therapeutic Perspectives—A Narrative Review

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Non‐motor symptoms, especially autonomic dysfunction, are major contributors to disability and decreased quality of life in Parkinson's disease (PD). Despite being common and having a wide range of clinical facets, exocrine gland dysfunction is still not well recognized and managed.
Renato P. Munhoz   +2 more
wiley   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

Review of nutrition management of pediatric intestinal pseudo‐obstruction

open access: yesNutrition in Clinical Practice, EarlyView.
Abstract Chronic intestinal pseudo‐obstruction (CIPO) is a rare, heterogeneous, and debilitating disorder characterized by profound intestinal dysmotility and severe nutrition challenges. Its presentation resembles that of mechanical bowel obstruction, but CIPO occurs in the absence of luminal obstruction.
Senthilkumar Sankararaman   +5 more
wiley   +1 more source

Investigating the Relationship Human Parvovirus B19 Infection in Benign and Malignant Salivary Gland Tumors. [PDF]

open access: yesJ Dent (Shiraz)
Farhadi A   +4 more
europepmc   +1 more source

Innate immunity shapes the persistent transmission of plant viruses by insect vectors

open access: yesNew Plant Protection, EarlyView.
In this review, we focus on two key aspects of the virus–vector interplay: (1) persistently transmitted viruses utilize host factors to overcome transmission barriers; and (2) molecular recognition activates antiviral immunity and subsequent viral counter‐defense. Understanding these interactions offers critical insights for developing novel strategies
Gang Lu, Chuanxi Zhang, Junmin Li
wiley   +1 more source

Decisional Conflict in Palliative Head and Neck Cancer Patients

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Head and neck cancer (HNC) patients may be subject to decisional conflict (DC). However, research on DC in the palliative phase remains limited. The primary objective of this study was to assess and describe DC among patients with HNC in the palliative phase and explore the association between clinically significant DC and quality of
Boyd N. van den Besselaar MD   +4 more
wiley   +1 more source

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