Results 151 to 160 of about 24,975 (291)

Glucocorticoids and HPA axis regulation in the stress–obesity connection: A comprehensive overview of biological, physiological and behavioural dimensions

open access: yesClinical Obesity, Volume 15, Issue 2, April 2025.
Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton   +4 more
wiley   +1 more source

Hypoxia Exacerbates Periapical Periodontitis‐Associated Pathological Bone Loss via the Hypoxia‐Inducible Factor‐2α‐Calmodulin‐Dependent Protein Kinase IV Axis

open access: yesCell Proliferation, EarlyView.
Hypoxia exposure activates HIF‐2α, which binds to the Camk4 promoter to enhance RANKL‐mediated osteoclast differentiation, leading to aggravated alveolar bone resorption in periapical periodontitis. ABSTRACT Periapical periodontitis is one of the most common inflammatory bone destructive diseases. Epidemiological evidence suggests that hypoxia exposure,
Kang Gao   +11 more
wiley   +1 more source

Cytopathology Terminology Systems: European Federation of Cytological Societies Survey on Practice in Europe

open access: yesCytopathology, EarlyView.
Cytology terminologies are widely accepted within Europe based on EFCS survey. The Bethesda System for reporting cervical cytology and the Bethesda System for reporting thyroid cytopathology have been implemented by most of the responding countries. ABSTRACT Cytopathologists communicate with clinicians via cytopathology reports.
Ivana Kholová   +46 more
wiley   +1 more source

From Tumour to Bloodstream: Advancing PD‐L1 Testing With Liquid Biopsies in Non‐Small Cell Lung Cancer

open access: yesCytopathology, EarlyView.
This review explores liquid biopsy as a complementary approach to tissue‐based PD‐L1 assessment in advanced NSCLC treated with immune checkpoint inhibitors. Focusing on circulating tumour cells, extracellular vesicles, and circulating tumour DNA, it summarises current evidence, technical challenges, and future perspectives for personalised ...
R. Leporati   +15 more
wiley   +1 more source

Sialoblastoma of the Minor Salivary Glands: A Case Report. [PDF]

open access: yesCase Rep Dent
Novelli G   +5 more
europepmc   +1 more source

COVID‐19's Shadow: The Effect of COVID‐19 on Cytopathology Specimens Received at an Academic Laboratory in Central South Africa

open access: yesCytopathology, EarlyView.
Due to global COVID‐19‐related disruptions in healthcare delivery, cytopathology laboratories experienced a reduction in specimen volume that did not fully recover post‐COVID‐19. The findings of the study highlighted the importance of resilient diagnostic services during health crises.
Courtney T. A. Bonato   +2 more
wiley   +1 more source

Extranodal Marginal Zone Lymphoma: Integrating Etiology, Microenvironment, and Genetics Into Clinical Decision‐Making

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Extranodal marginal zone lymphoma (EMZL) represents a unique paradigm among indolent B‐cell neoplasms, in which lymphomagenesis is frequently driven by chronic antigenic stimulation within tissue‐specific microenvironments. Persistent infectious or autoimmune triggers promote the development of ectopic lymphoid tissue and sustain B‐cell ...
Mamdouh Skafi   +15 more
wiley   +1 more source

Effect of aging on healing of mandibular tooth extraction socket in a rat model

open access: yesEuropean Journal of Oral Sciences, EarlyView.
Abstract This study evaluated the effect of aging on bone regeneration in mandibular extraction sockets. Male Sprague–Dawley rats were divided into three age groups: 2‐month‐old (2 M, n = 6), 10‐month‐old (10 M, n = 6), and 18‐month‐old (18 M, n = 5). Two weeks post‐extraction, comprehensive analyses were performed using micro‐computed tomography (µ‐CT)
Kyung Su Shin   +7 more
wiley   +1 more source

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