Results 191 to 200 of about 20,328 (265)

Mechanisms of enhancer‐driven oncogene activation

open access: yesInternational Journal of Cancer, Volume 158, Issue 2, Page 333-341, 15 January 2026.
Abstract An aggressive subtype of acute myeloid leukemia (AML) is caused by enhancer hijacking resulting in MECOM overexpression. Several chromosomal rearrangements can lead to this: the most common (inv(3)/t(3;3)) results in a hijacked GATA2 enhancer, and there are several atypical MECOM rearrangements involving enhancers from other hematopoietic ...
Joyce Vriend   +2 more
wiley   +1 more source

A Case of Mucous Gland Adenoma of the Lung Representing NKX3.1-Positive Lung Tumour Spectrum. [PDF]

open access: yesRespirol Case Rep
Ishii K   +5 more
europepmc   +1 more source

Deregulated enhancer‐promoter communication in cancer through altered nuclear architecture

open access: yesInternational Journal of Cancer, Volume 158, Issue 2, Page 409-422, 15 January 2026.
Abstract Enhancers are critical regulators of gene expression. Structural variations in cancer genomes can lead to enhancer hijacking, where oncogenes are activated by mistargeted enhancer activity. Novel enhancer‐promoter interactions may also arise through chromosomal rearrangements that create extrachromosomal DNA elements.
Isabelle Seufert   +3 more
wiley   +1 more source

Clinical presentation, surgical management, and long-term outcomes of pharyngeal sialoceles in dogs: 6 cases (2015-2025). [PDF]

open access: yesBMC Vet Res
Tsioli V   +6 more
europepmc   +1 more source

Correlated Expression of Notch2 and ADAM17 in Primary Sjögren's Syndrome Salivary Glands. [PDF]

open access: yesJ Clin Med
Sisto M   +8 more
europepmc   +1 more source

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