Results 171 to 177 of about 6,962 (177)

First-in-human PET imaging and evaluation of melanin-targeted [¹⁸F]DMPY2 in malignant melanoma patients. [PDF]

Theranostics
Yang Y, Zhou M, Zhao S, Long T, Chen N, Wang X, Li Y, Chen X, Chen J, Huang X, Chen D, Su J, Hu S, Chen X.   +13 more
europepmc   +1 more source

Positron Emission Tomography-Magnetic Resonance Imaging, a New Hybrid Imaging Modality for Dentomaxillofacial Malignancies-A Systematic Review. [PDF]

Diagnostics (Basel)
Mitsea A, Christoloukas N, Koutsipetsidou S, Papavasileiou P, Oikonomou G, Angelopoulos C.   +5 more
europepmc   +1 more source

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Comparing the gastric emptying of 240 mL and 20 mL water by MRI and caffeine salivary tracer technique

European Journal of Pharmaceutics and Biopharmaceutics, 2023
Gastrointestinal fluid volumes are a crucial parameter for dissolution and absorption of orally taken medications. Most often 240 mL are used in clinical standard setups. Nonetheless, surveys in patient populations revealed dramatically lower volumes for intake of oral medications in real life and even in some clinical studies reduced fluid volumes are
Michael Grimm, Philipp Aude, Maximilian Feldmüller, Rebecca Keßler, Eberhard Scheuch, Mladen V. Tzvetkov, Mirko Koziolek, Werner Weitschies   +7 more
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Combined Application of MRI and the Salivary Tracer Technique to Determine the in Vivo Disintegration Time of Immediate Release Formulation Administered to Healthy, Fasted Subjects

Molecular Pharmaceutics, 2019
The process of disintegration is a crucial step in oral drug delivery with immediate release dosage forms. In this work, the salivary tracer technique was applied as a simple and inexpensive method for the investigation of the in vivo disintegration time of hard gelatin capsules filled with caffeine.
Maximilian Sager, Michael Grimm, Philipp Jedamzik, Simon Merdivan, Marie-Luise Kromrey, Mahmoud Hasan, Mirko Koziolek, Mladen V. Tzvetkov, Werner Weitschies   +8 more
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In vivo characterization of enTRinsic™ drug delivery technology capsule after intake in fed state: A cross-validation approach using salivary tracer technique in comparison to MRI

Journal of Controlled Release, 2019
The instability of various small molecules, vaccines and peptides in the human stomach is a complex challenge for oral drug delivery. Recently, a novel gastro-resistant capsule - the enTRinsic™ Drug Delivery Technology capsule - has been developed.
Maximilian Sager, Michael Grimm, Philipp Aude, Philipp Schick, Simon Merdivan, Mahmoud Hasan, Marie-Luise Kromrey, Aurélien Sivert, Hassan Benameur, Mirko Koziolek, Mladen V. Tzvetkov, Werner Weitschies   +11 more
openaire   +2 more sources