Results 81 to 90 of about 22,611 (205)

Deprescription of Psychotropics in Children and Adolescents: Systematic Review of Guidelines and Development of a Deprescribing Algorithm

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 139, Issue 3, September 2026.
ABSTRACT Background Psychotropics are increasingly prescribed in paediatrics despite limited evidence regarding their benefits and effectiveness. Although deprescribing approaches are established in adults, structured paediatric strategies remain poorly defined.
Paul‐Benoît Fargier   +6 more
wiley   +1 more source

Genistein and Naringenin as Defense Molecules

open access: yesMolecules
Genistein and naringenin, plant phenolic compounds, are recognized for their health benefits and role in plant defense against herbivores. However, little research exists on how these compounds affect aphid feeding, particularly that of the black bean ...
Sylwia Goławska   +2 more
doaj   +1 more source

Factors Associated with Hyposalivation in Brazilian Adults

open access: yesPesquisa Brasileira em Odontopediatria e Clínica Integrada, 2023
Objective: To determine the occurrence of hyposalivation in Brazilian adults and its association with individual determinants, such as the use of medications, systemic conditions, smoking, and alcohol consumption.
Handerson Nunes de Carvalho   +6 more
doaj  

Impact of TCAs and Gabapentin on Saliva and BMI in Adults With Xerostomia

open access: yesJournal of Oral Rehabilitation, Volume 53, Issue 9, Page 1694-1702, September 2026.
In adults with medication‐related xerostomia, tricyclic antidepressant and gabapentin use were not independently associated with BMI or oral dryness after adjustment. Instead, female sex, anticholinergic burden, obstructive sleep apnea, GERD, thyroid disease, depression and race demonstrated stronger associations with reduced salivary flow and greater ...
Waldir Martineli Filho   +5 more
wiley   +1 more source

Modulating Taste Perception in Newly Weaned Piglets: The Role of Palatability Additives in Enhancing Feed Intake and Performance

open access: yesAnimal Research and One Health, Volume 4, Issue 3, Page 240-246, August 2026.
Palatability enhancers modulate taste and smell, increasing feed acceptance, reducing weaning stress, and improving piglet performance. ABSTRACT The continuous growth of global agribusiness stimulates the search for alternatives that can enhance the performance and quality of life of production animals.
Luana Specht   +3 more
wiley   +1 more source

Pharmacological Assessment of Calamus guruba Methanolic Extract: Multitarget Effects on Diabetes, Inflammation, Anxiety, and Depression

open access: yesFood Science &Nutrition, Volume 14, Issue 8, August 2026.
Calamus guruba Buch.‐Ham. (family Arecaceae) is a highly regarded traditional medicinal plant known for its diverse therapeutic benefits. This research aimed to investigate the antidiabetic, anti‐inflammatory, anxiolytic, and antidepressant effects of the methanolic extract of C. guruba (MECG).
Mohi Uddin   +5 more
wiley   +1 more source

The Role of Bitter-Tasting Substances in Salivation and Swallowing: Results of the Pilot Study

open access: yesFoods
The aim of this study was to investigate the effects of caffeine, vanillin, and epigallocatechin gallate on salivation and swallowing and to find ways to correct their negative effects. Solutions of these substances with an equivalent intensity of bitter
Ekaterina Oganesiants   +4 more
doaj   +1 more source

Goniothalamin as a Styryl‐Lactone Toxicophore in Cancer Models: Electrophile‐Driven DNA Damage, Reactive Oxygen Species–Endoplasmic Reticulum Stress Signaling and Detoxification‐Relevant Safety Considerations

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Goniothalamin (GTN) exerts anticancer effects by promoting reactive oxygen species (ROS) generation, glutathione (GSH) depletion, DNA damage, endoplasmic reticulum (ER) stress, and mitochondrial dysfunction. These interconnected events trigger apoptosis, necroptosis, anoikis, and autophagy, while modulating mitogen‐activated protein kinase (MAPK ...
Nataša Joković   +6 more
wiley   +1 more source

Error Traps in Pediatric Neuromuscular Block

open access: yesPediatric Anesthesia, Volume 36, Issue 8, Page 887-898, August 2026.
ABSTRACT Background Neuromuscular blocking agents are essential for safe pediatric anesthesia but remain a frequent source of preventable morbidity when misused, inadequately monitored, or incompletely reversed. Children, particularly neonates and infants, are especially vulnerable to residual neuromuscular block due to developmental pharmacological ...
Gabriel Soares de Sousa   +5 more
wiley   +1 more source

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