Results 271 to 280 of about 3,422,852 (337)

Advances in the Study of Pluripotent Stem Cells in Livestock

open access: yesCell Proliferation, EarlyView.
Livestock pluripotent stem cells include embryonic stem cells (ESCs) isolated from the inner cell mass of blastocysts and induced pluripotent stem cells (iPSCs) derived from somatic cell reprogramming. They hold significant potential for applications in livestock breed improvement, rapid propagation, human disease modelling and human organ ...
Xinyi Zhou   +6 more
wiley   +1 more source

Concurrent Ascaris infection modulates host immunity resulting in impaired control of Salmonella infection in pigs. [PDF]

open access: yesmSphere
Midha A   +17 more
europepmc   +1 more source

Dual Role of Natural Killer Cells in Early Pregnancy: Immunopathological Implications and Therapeutic Potential in Recurrent Spontaneous Abortion and Recurrent Implantation Failure

open access: yesCell Proliferation, EarlyView.
This article elaborates on the role of NK cells in early pregnancy from multiple perspectives, including molecular mechanisms and therapeutic interventions. It also discusses how NK cell dysfunction contributes to RSA and RIF, aiming to provide insights for future research on NK cell mechanisms and clinical treatment of RSA and RIF.
Defeng Guan   +5 more
wiley   +1 more source

Molecular detection of pathogens in an equine fever diagnostic panel: 2019–2023

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background A common diagnostic approach for febrile horses is to test for a panel of potential pathogens. Panels are curated by expert opinion and vary between diagnostic laboratories. Objectives To report the results of a newly developed equine fever diagnostic panel (EFDP) between 2019 and 2023 and evaluate the frequency of positive results.
Toby L. Pinn‐Woodcock   +3 more
wiley   +1 more source

A loop‐mediated isothermal amplification assay to detect insect‐associated Serratia spp. in the critically endangered insect Dryococelus australis

open access: yesInsect Conservation and Diversity, EarlyView.
Inclusion of a novel sample cleanup step prior to extraction of bacterial DNA from insect frass enhanced rates of bacterial cell recovery and removed insect and plant cells. Development of a robust LAMP assay allowed detection of insect‐associated members of the Serratia marcescens complex in frass from live insects. Results from the LAMP assay applied
Nicholas P. Doidge   +5 more
wiley   +1 more source

Innate Immune Activation Is a Strong Suppressor of CCL22 and Impedes Regulatory T Cell–Dendritic Cell Interaction

open access: yesImmunology, EarlyView.
During homeostasis, CCL22 is secreted by dendritic cells (DC), which mediate contacts between regulatory T cells (Treg) and DC to maintain immune balance. Activation of innate immunity via microbes or pattern recognition receptor (PRR) agonists induces the secretion of several soluble factors (e.g., type I and II interferons, IL‐10), which mediate ...
Ignazio Piseddu   +24 more
wiley   +1 more source

Salmonella Heidelberg Infection in Caroli's Syndrome

open access: bronze, 1975
R Waldram, J. Vahrman, Roger Williams
openalex   +1 more source

Flagellins as Vaccine Adjuvants and Cancer Immunotherapy: Recent Advances and Future Prospects

open access: yesImmunology, EarlyView.
The figure depicts the role of flagellin in immune cells. Flagellin interacts with TLR5, resulting in the formation of homodimers and the recruitment of MyD88, which activates the IκB and MAPK signalling pathways. This results in the activation of NF‐κB and AP‐1, producing TNF‐α, IL‐6, IL‐8, and IL‐12.
Asma Talukder   +4 more
wiley   +1 more source

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