Results 41 to 50 of about 231,792 (205)

Target identification for prevention and therapy of "Salmonella" infections [PDF]

, 2014
In this thesis we investigated maintenance requirements of Salmonella during chronic infections, and determined the relevant antigen properties that might facilitate the development of Salmonella vaccines. Overall, we wanted to achieve two goals: a)To
Barat, Somedutta
core   +1 more source

Comparative evaluation of planktonic and biofilm modes of growth in Salmonella Typhimurium [PDF]

, 2011
In this research, comparative studies of planktonic and biofilm modes of growth in Salmonella enterica serovar Typhimurium were undertaken. Chemical disinfectant studies were performed for both planktonic and biofilm Salmonella and biofilms at different ...
Wong, Hui San
core  

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Wearable Smart Patches on Sustainable Chitosan With Reversible Microbial Growth‐Inhibitory Properties

Advanced Functional Materials, EarlyView.
ABSTRACT Chitosan, a polysaccharide upcycled from biowaste, has long promised sustainable, biocompatible, and antimicrobial films and devices, an appeal reinforced by its recent regulatory recognition, with several chitosan‐based antibacterial dressings gaining clearance through the Food and Drug Administration's 510(k) pathway.
Jacopo Nicoletti, Kubra Kocak, Andrea Michel, Enrico Cavarzerani, Ali Raza, Petr Rohzin, Nouha Loudhaief, Saimir Frroku, Nicolò Baldovin, Hazrat Bilal, Alvise Perosa, Maurizio Selva, Flavio Rizzolio, Luca Sbuelz, Sabrina Tamburini, Domenico De Fazio, Giovanni Antonio Salvatore   +16 more
wiley   +1 more source

RhoB promotes Salmonella survival by regulating autophagy

European Journal of Cell Biology, 2023
Salmonella enterica serovar Typhimurium manipulates cellular Rho GTPases for host cell invasion by effector protein translocation via the Type III Secretion System (T3SS).
Marco Kirchenwitz, Jessica Halfen, Kristin von Peinen, Silvia Prettin, Jana Kollasser, Susanne zur Lage, Wulf Blankenfeldt, Cord Brakebusch, Klemens Rottner, Anika Steffen, Theresia E.B. Stradal   +10 more
doaj   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

T-2 toxin induced Salmonella Typhimurium intoxication results in decreased Salmonella numbers in the cecum contents of pigs, despite marked effects on Salmonella-host cell interactions

Veterinary Research, 2012
The mycotoxin T-2 toxin and Salmonella Typhimurium infections pose a significant threat to human and animal health. Interactions between both agents may result in a different outcome of the infection.
Verbrugghe Elin, Vandenbroucke Virginie, Dhaenens Maarten, Shearer Neil, Goossens Joline, De Saeger Sarah, Eeckhout Mia, D'Herde Katharina, Thompson Arthur, Deforce Dieter, Boyen Filip, Leyman Bregje, Van Parys Alexander, De Backer Patrick, Haesebrouck Freddy, Croubels Siska, Pasmans Frank   +16 more
doaj   +1 more source

A rapid change in virulence gene expression during the transition from the intestinal lumen into tissue promotes systemic dissemination of Salmonella. [PDF]

, 2010
Bacterial pathogens causing systemic disease commonly evolve from organisms associated with localized infections but differ from their close relatives in their ability to overcome mucosal barriers by mechanisms that remain incompletely understood.
Rüssmann Holger, Sebastian E. Winter, Andrews-Polymenis Helene L., Bäumler Andreas J., Winter Sebastian E., Andreas J. Bäumler, Yang, Hee-Jeong, Godinez, Ivan, Fierer, Joshua, Winter, Maria G., Helene L Andrews-Polymenis, Helene L. Andrews-Polymenis, Winter, Sebastian E., Winter Maria G., Maria G. Winter, Sebastian E Winter, Bäumler, Andreas J., Holger Rüssmann, Hee-Jeong Yang, Andrews-Polymenis, Helene L., Andreas J Bäumler, Yang Hee-Jeong, Maria G Winter, Rüssmann, Holger, Ivan Godinez, Godinez Ivan   +25 more
core   +1 more source

Radiation‐Triggered Chemokine‐Secreting Probiotics for Boron Neutron Capture Therapy Based Radioimmunotherapy

Advanced Science, EarlyView.
Engineered Escherichia coli Nissle 1917 with a tannic acid‐mediated BPA coating enables tumor‐targeted boron delivery for BNCT. The low‐level incidental radiation generated during BNCT activate a RecA‐driven circuit to induce CXCL10, while radiation‐enhanced bacterial colonization triggers in situ vaccination and systemic antitumor immunity.
Yang Liu, Yuzhong Qian, Shaobo Huang, Bingbing Li, Yue Yu, Xiang Cheng, Chang Chen, Jiheng Wang, Maosong Yang, Lizheng Liang, Xiancai Meng, Zhigang Liu   +11 more
wiley   +1 more source

Salmonella Typhimurium infection: Type I Interferons integrate cellular networks to disintegrate macrophages [PDF]

, 2018
Type I interferons have immunomodulatory functions during infection with bacteria and viruses. They are vital for the host defense against viruses and extracellular bacteria. However, recent evidences show that IFN-I contributes to immunopathology during
Robinson, N., Nirmal Robinson
core   +1 more source