Results 61 to 70 of about 1,531,335 (318)
Sexually Transmitted Infections, 2001 “Rob, I know you're a doctor—can I have a word about your son.” The reception class nursery nurse's words chilled me to the bone, as Jamie (aged 5) had been off colour for a few days. “I am a bit worried about the rash he has got on his face. Three other children in the class have a similar rash—do you think it is infectious?” I looked at the bright ...
openaire +2 more sources
Salt Lake County Library System Historical Scrapbook, 1970-1972
, 1970 Salt Lake County Library System Historical ...
Salt Lake County (Utah). Library System
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Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Salt Lake County Library System Historical Scrapbook, 1980(b)
, 1980 Salt Lake County Library System Historical ...
Salt Lake County (Utah). Library System
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Cobalt+Salt-Stressed Salvia officinalis: ROS Scavenging Capacity and Antioxidant Potency
International Journal of Secondary Metabolite, 2019 Salvia officinalis L. (Lamiaceae) is one of the most widespread herbal species used in the food processing industry and for culinary and medicinal purposes.
Hülya Torun
doaj +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Salt Lake County Library System Historical Scrapbook, 1973-1974
, 1973 Salt Lake County Library System Historical ...
Salt Lake County (Utah). Library System
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Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Salt Lake County Library System Historical Scrapbook, 1981-1982
, 1981 Salt Lake County Library System Historical ...
Salt Lake County (Utah). Library System
core
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source