Results 41 to 50 of about 737,699 (340)
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
Molecular Oncology, EarlyView.CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak +14 more
wiley +1 more source
Are calcareous soil ecosystems and associated drainage waters less susceptible to damage from winter road salting than acidic soil ecosystems? [PDF]
, 2008 Previous studies of upland roadside soils in Cumbria, that would normally be naturally acidic, have highlighted that (a) runoff from roads subjected to long-term road salting can dramatically raise soil pH down slope in upland areas; (b) the soil pH ...
Cresser, M.S., Green, S.M.
core +1 more source
Membranes, 2022 Lipid droplets are essential organelles that store and traffic neutral lipids. The phospholipid monolayer surrounding their neutral lipid core engages with a highly dynamic proteome that changes according to cellular and metabolic conditions. Recent work
R. Jay Braun, Jessica M. J. Swanson
doaj +1 more source
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren +16 more
wiley +1 more source
Input and output considerations in estimating rates of chemical denudation [PDF]
, 1970 Estimation of rates of solutional denudation in river basins necessitates some consideration of salt inputs as well as consideration of salt outputs.
Goudie, Andrew
core +1 more source
A Review on the Salt Bridge Between ASP177 and ARG163 of Wild-Type Rabbit Prion Protein
, 2015 Prion diseases are invariably fatal and highly infectious neurodegenerative diseases that affect a wide variety of mammalian species such as sheep and goats, cattle, deer, elks, humans and mice etc., but rabbits have a low susceptibility to be infected ...
Wang, Feng, Zhang, Jiapu
core +2 more sources
Molecular Oncology, EarlyView.Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho +11 more
wiley +1 more source
Spatial variability of climate and past atmospheric circulation patterns from central West Antarctic glaciochemistry [PDF]
, 1999 Atmospheric circulation patterns and the spatial variability of atmospheric chemistry and moisture transport in central West Antarctica are investigated using new 40 year long (1954–1994 A.D.) glaciochemical and accumulation rate records developed from ...
Mayewski, Paul A. +4 more
core +3 more sources
Attractive forces in microporous carbon electrodes for capacitive deionization [PDF]
, 2013 The recently developed modified Donnan (mD) model provides a simple and useful description of the electrical double layer in microporous carbon electrodes, suitable for incorporation in porous electrode theory.
Bazant, M. Z. +3 more
core +4 more sources
Salts of Therapeutic Agents: Chemical, Physicochemical, and Biological Considerations
Molecules, 2018 The physicochemical and biological properties of active pharmaceutical ingredients (APIs) are greatly affected by their salt forms. The choice of a particular salt formulation is based on numerous factors such as API chemistry, intended dosage form ...
Deepak Gupta +4 more
doaj +1 more source