Zinc Finger Readers of Methylated DNA
Molecules, 2018 DNA methylation is a prevalent epigenetic modification involved in regulating a number of essential cellular processes, including genomic accessibility and transcriptional outcomes.
Nicholas O. Hudson +1 more
doaj +1 more source
LIN28B Promotes Cancer Cell Dissemination and Angiogenesis
Advanced Biology, EarlyView.Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo +8 more
wiley +1 more source
Plasmodium falciparum glyoxalase II: Theorell-Chance product inhibition patterns, rate-limiting substrate binding via Arg(257)/Lys(260), and unmasking of acid-base catalysis [PDF]
, 2009 Glyoxalase II (GloII) is a ubiquitous thioester hydrolase catalyzing the last step of the glutathione-dependent conversion of 2-oxoaldehydes to 2-hydroxycarboxylic acids.
Elia A.C. +6 more
core +1 more source
Heliyon, 2023 Among the variety of energy storage techniques thermal energy storage (TES), based on molten salts, is already in use for the storage of heat in a gigawatt hour scale.
Sebastian Kunkel +4 more
doaj
Advanced Biology, EarlyView.In this study, a new type of bioactive glass fiber ‐based composite magnesium phosphate bone cement is prepared and verified that its mechanical strength and biological properties. In addition, the cement may have played a biologically active role in the Notch and HIF signaling pathways.
Yuzheng Lu +12 more
wiley +1 more source
The interpretation of spikes and trends in concentration of nitrate in polar ice cores, based on evidence from snow and atmospheric measurements [PDF]
, 2008 Nitrate is frequently measured in ice cores, but its interpretation remains immature. Using daily snow surface concentrations of nitrate at Halley (Antarctica) for 2004 - 2005, we show that sharp spikes (> factor 2) in nitrate concentration can occur ...
Bauguitte, S.J.-B. +3 more
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PENGENALAN ILMU PENGETAHUAN ALAM MELALUI DEMONSTRASI SEDERHANA
Faktor Exacta, 2016 This article focus on the discussion of “instructional chemistry economic-based” Chemistry work is a students’ learning process which is constructed by teachers to develop creative thinking, so it can improve the ability to build a new knowlege and to ...
NURDENI NURDENI +1 more
doaj +1 more source
The Regulation of Trace Metal Elements in Cancer Ferroptosis
Advanced Biology, EarlyView.The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang +5 more
wiley +1 more source
Hydrologic and chemical analysis of salt ponds on St. John, U.S. Virgin Islands [PDF]
, 2003 Thesis (M.Eng.)--Massachusetts Institute of Technology, Dept. of Civil and Environmental Engineering, 2003.Includes bibliographical references (p. 81-83).In order to assess the impact of human development on salt ponds, this study investigated the ...
Bossi, Liam, 1979-, Rose, Donald, 1978-
core
The stability and activity of human neuroserpin are modulated by a salt bridge that stabilises the reactive centre loop [PDF]
, 2015 Neuroserpin (NS) is an inhibitory protein belonging to the serpin family and involved in several pathologies, including the dementia Familial Encephalopathy with Neuroserpin Inclusion Bodies (FENIB), a genetic neurodegenerative disease caused by ...
Caccia, Sonia +7 more
core +1 more source