Results 81 to 90 of about 2,407,051 (386)

Changes in dissolved iron deposition to the oceans driven by human activity: a 3-D global modelling study [PDF]

, 2015
The global atmospheric iron (Fe) cycle is parameterized in the global 3-D chemical transport model TM4-ECPL to simulate the proton- and the organic ligand-promoted mineral-Fe dissolution as well as the aqueous-phase photochemical reactions between the ...
Baker, Alex, Daskalakis, Nikos, Kanakidou, Maria, Mihalopoulos, Nikos, Myriokefalitakis, Stelios, Nenes, Athanasios   +5 more
core   +2 more sources

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Exploring the scope of DBU-promoted amidations of 7-carboxymethyl-pterin [PDF]

, 2020
Pteridines are an important heterocycle often used in the development of pharmaceutically relevant compounds, and in the field of supramolecular chemistry.
Bockman, Anna
core   +1 more source

Activity of water in aqueous systems; A frequently neglected property [PDF]

, 2005
In this critical review, the significance of the term ‘activity’ is examined in the context of the properties of aqueous solutions. The dependence of the activity of water(ℓ) at ambient pressure and 298.15 K on solute molality is examined for aqueous ...
Blandamer, Mike J.,, Engberts, Jan B.F.N.,, Gleeson, Peter T.,, Reis, João Carlos R.,   +3 more
core   +2 more sources

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Supplemental Material: New age and lake chemistry constraints on the Aptian pre-salt carbonates of the central South Atlantic [PDF]

, 2022
Michael Lawson, et al.
openalex   +2 more sources

Region-specific defect engineering of Bi2W1-xO6-γ induces nanoscale electric fields and surface active-sites for enhanced visible-light oxidation of salt-lake flotation agents

Nature Communications
Breaking the limitations of conventional defect engineering, this work pioneers region-specific dual-defect engineering in Bi2WO6. By precisely tailoring tungsten (W) and oxygen (O) vacancies at nanoscale spatial domains-W vacancies at the edges and O ...
Liang Ma, Siyuan Zhang, Haining Liu, Chunyan Wang, Zhongmei Song, Wenjie Han, Mingzhe Dong, Jungang Hou, Weidong Shi, Xiushen Ye   +9 more
doaj   +1 more source

Molecular basis of pigment structural diversity in echinoderms

iScience
Summary: The varied pigments found in animals play both ecological and physiological roles. Virtually all echinoderms contain putative pigment biosynthetic enzymes, the polyketide synthases (PKSs).
Feng Li, Zhenjian Lin, Eric W. Schmidt
doaj   +1 more source

Types and properties of metal-free catalysts for living polymerizations of biomaterials [PDF]

, 2008
Syntéza biokompatibilních a biodegradabilních polyesterů, použitelných převážně v medicíně, využívá pro polymeraci za otevření kruhu katalyzátory na bázi kovu (např. Sn, Al atd.), které se mohou po implantaci deponovat v těle.
Repka, Martin
core  

Nitrile-assistant eutectic electrolytes for cryogenic operation of lithium ion batteries at fast charges and discharges [PDF]

, 2014
The charge/discharge characteristics of lithium ion batteries at low temperature (LT = -20 ??C) are enhanced by using ethylene carbonate (EC)-based electrolytes with the help of assistant solvents of nitriles. Conventional liquid electrolytes (e.g.
Abu-Lebdeh, Abu-Lebdeh, Bak, Brunet, Ding, Ding, Ding, Dong-Gil Sung, Duncan, Gering, Hyun-Kon Song, Kamaya, Kim, Kim, Lee, Myung-Su Seo, Ruiz, Sazhin, Shiao, Smart, Smart, Smart, Smart, Smart, Smart, Wang, Yoon-Gyo Cho, Young-Soo Kim, Zhang   +28 more
core   +1 more source