Results 81 to 90 of about 505,868 (313)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

The use of sodium salt deposits in medical and medically associated industries in Ancient Egypt [PDF]

, 2009
The utilisation of minerals in Ancient Egyptian medicine from procurement through to use is examined here in a case study investigating the role of sodium salts. The sodium salts, salt and natron are two of the three most commonly used minerals in the
Sapsford, M.
core  

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Introduction of nanofiltration in a production process of fermented organic acids [PDF]

, 2004
Nanofiltration in a production process of fermented organic ...
Roux-de Balmann, Hélène, Lutin, Florence, Bouchoux, Antoine   +2 more
core  

The Strategy of Welfare Improvement for Salt Farmers in Indonesia

MATEC Web of Conferences, 2018
Until now, production of salt in Indonesia is done by salt farmers and PT. Garam Indonesia as the only state company that produces salt. As the perpetrators of production which contribute greatly to the national salt production, salt farmer is considered
Sudaryana Bambang, Pramesti Puji
doaj   +1 more source

SITE SUITABILITY ANALYSIS OF SALT FARMS IN PANGASINAN USING GEOSPATIAL DATA AND ANALYTIC HIERARCHY PROCESS [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences
The Philippines has imported 93% (550,000 MT) of its annual salt requirement in 2020. Such heavy reliance on salt importation may be attributed to the two decades of neglect and steady downward production trend of the local salt industry. There is a need
A. J. D. C. Carrido, J. S. R. Melgarejo, J. A. Principe, J. A. Principe, J. M. Medina, J. M. Medina   +5 more
doaj   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Effects of Salt Stress on Physiological and Agronomic Traits of Rice Genotypes with Contrasting Salt Tolerance [PDF]

Salinity is one of the major constraints to crop production. Rice is a main staple food and is highly sensitive to salinity. This study aimed to elucidate the effects of salt stress on physiological and agronomic traits of rice genotypes with contrasting
Yuchao Xu, Irshad Ahmad, Weicheng Bu, Guisheng Zhou, Yiming Zhu, Guanglong Zhu, Yunming Xu, Nimir Eltyb Ahmed Nimir, Han Fei   +8 more
core   +1 more source