Results 151 to 160 of about 394,652 (294)

Electrical Impedance Myography Detects Disease Progression over 12 to 24 Months in Facioscapulohumeral Muscular Dystrophy

open access: yesAnnals of Neurology, EarlyView.
Objective Targeted therapies for facioscapulohumeral muscular dystrophy (FSHD) are progressing through clinical trials. Electrical impedance myography (EIM) provides a noninvasive biomarker of muscle composition that may be valuable especially in early phase trials. This study evaluated EIM data from a multicenter FSHD cohort over 24 months.
Karlien Mul   +15 more
wiley   +1 more source

NUAK2 Inhibition Enhances Macromolecular Drug Delivery in a 3D Fibrotic Model of the Pancreatic Tumor Microenvironment

open access: yesAdvanced NanoBiomed Research, EarlyView.
Using a 3D cell culture model of the fibrotic barrier in pancreatic cancer, this work shows that inhibiting NUAK2 kinase in pancreatic stellate cells enhances macromolecular drug delivery. Mechanistically, NUAK2 inhibition disrupted actin stress fiber assembly to downregulate collagen I expression, thus enhancing macromolecular permeability.
Misaki Nakamura   +14 more
wiley   +1 more source

De novo Membranous Nephropathy in Renal Allografts is Associated With Protocadherin FAT1

open access: yesKidney International Reports
Laith F. Al-Rabadi   +17 more
doaj   +1 more source

Rational Formulation of Ether‐Lactone Electrolytes for Safe and Sustainable Ni‐Rich Lithium‐Ion Batteries

open access: yesAngewandte Chemie International Edition, EarlyView.
This study reports the formulation of innovative electrolytes to improve safety, sustainability, and compatibility with Ni‐rich cathodes through the use of a bio‐based solvent (γ‐valerolactone, GVL) and a safe, stable, innovative co‐solvent (diethylene glycol butyl ethyl ether, DEGBEE).
Juan Luis Gómez‐Urbano   +17 more
wiley   +1 more source

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