Results 41 to 50 of about 178,309 (310)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

COMPARISON OF GEO-MECHANICAL PROPERTIES OF WHITE ROCK SALT AND PINK ROCK SALT IN KŁODAWA SALT DIAPIR [PDF]

open access: yesStudia Geotechnica et Mechanica, 2013
Abstract Within the boundaries of the Salt Mine “Kłodawa”, rock-salts and potassium-magnesium salts occur at different stratigraphic levels. The present article introduces strength-strain properties of white rock salt, building the nucleus of northeastern edge anticline, and pink rock salt that belongs to the series of youngest rock salt.
Malwina Kolano, Danuta Flisiak
openaire   +1 more source

Influence of storage layout on stability of horizontal storage group in bedded salt rocks

open access: yesYou-qi chuyun, 2022
With the rapid development of China's economy and society in recent years, the demand for oil and natural gas is growing day by day, and a large number of underground energy reserves have begun to be built in salt rocks.
Xue BAI   +4 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Karst, GIS and geological hazard planning and management in Great Britain [PDF]

open access: yes, 2010
The British Geological Survey (BGS) database of karst features for the United Kingdom include dolines, cave entrances, stream sinks, resurgences and building damage; data for approximately half of the country has so far been gathered.
Cooper, A.H., Farrant, A.R., Price, S.J.
core  

SALINITY OF SOILS OF INTERMOUNTAIN DEPRESSIONS IN THE DESERTS OF THE ZALTAI GOBI OF MONGOLIA

open access: yesБюллетень Почвенного института им. В.В. Докучаева, 2010
Intermountain depressions (depressions) are a characteristic feature of Zaaltai Gobi landscapes in Mongolia. There are three types of depressions, each of which is characterized by peculiarities of soil structure and specificity of soil salinity.
E. Pankova
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Enhanced Superconductivity in Rock-Salt TiO [PDF]

open access: yesACS Omega, 2017
Oxygen stoichiometry is critical for physical properties, but it is hard to precisely control in many multivalent transition metal oxides, for example, cuprate superconductors, magnetoresistive manganite oxides, and TiO x (x < 2). We have developed a new method to synthesize rock-salt TiO in a sealed and evacuated quartz tube by using KClO4 as the only
Dong Wang   +5 more
openaire   +3 more sources

Fault dislocations as fluid barriers of hydrocarbon deposits near salt domes in the Dnipro-Donets Depression, Ukraine

open access: yesGeo&Bio
Within the Dnipro-Donets aulacogen, Devonian salt stocks (diapirs) are widely developed. The suprastock, interstock, and nearstock areas associated with these diapirs have consistently drawn the interest of researchers in the Dnipro-Donets Depression for
Andrey Yakovlev, Iryna Samchuk
doaj   +1 more source

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

open access: yesArthritis Care &Research, EarlyView.
Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo   +88 more
wiley   +1 more source

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