Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto +11 more
wiley +1 more source
TaCML49-B, a Calmodulin-like Protein, Interacts with TaIQD23 to Positively Regulate Salt Tolerance in Wheat. [PDF]
Ru J +10 more
europepmc +1 more source
Phase separation organizes cellular components, yet stabilizing such dynamic structures in artificial cells remains challenging. A photo‐crosslinking approach is presented that prolongs the lifetime of different structures in coacervate‐based artificial cells while maintaining dynamic formation.
Madelief A. M. Verwiel +4 more
wiley +1 more source
ZmWRKY104-ZmCCaMK interaction enhances brassinosteroid-promoted salt tolerance in maize (<i>Zea mays</i> L.) via antioxidant defense. [PDF]
Zhao LL.
europepmc +1 more source
Principles for Rigorous Design and Application of Synthetic Microbial Communities
SynComs are artificially designed to enable inter‐species metabolic interactions, metabolic division of labor, and ecological interactions that can elicit phenotypes like colonization stability and environmental adaptation. This systematic review explores the processes used to construct SynComs, the assessment of the mechanisms of metabolic interaction
Yuxiao Zhang +21 more
wiley +1 more source
Heavy ion beam-induced variation in salt tolerance among <i>Leymus chinensis</i> genotypes during seed germination. [PDF]
Chen S +7 more
europepmc +1 more source
This study presents S‐coordinated Cu single‐atom nanozymes (Cu/CNS) fabricated via mild photocatalytic self‐assembly strategy. The nanozyme exhibits exceptional multi‐enzyme activity and near‐perfect antimicrobial efficacy. Incorporated into chitosan‐gelatin film, it enables pH‐responsive, broad‐spectrum fruit preservation, more than doubling the shelf‐
Chuanlong Men +7 more
wiley +1 more source
Expression of the <i>Suaeda salsa SsNLP7</i> Transcription Factor in <i>Solanum lycopersicum</i> Enhances Its Salt Tolerance. [PDF]
Cui C +5 more
europepmc +1 more source
GbWAKL20 Phosphorylates GbNFYB8 to Modulate Verticillium Wilt Resistance in Cotton
Wall‐associated receptor‐like kinases (WAKLs) play pivotal roles in extracellular–intracellular signal transduction. Upon sensing Verticillium dahliae infestation at the plasma membrane, GbWAKL20 accumulates and transmits signals to the nucleus via endoplasmic reticulum‐mediated Golgi vesicle transport.
Guilin Wang +7 more
wiley +1 more source

