Results 241 to 250 of about 24,661 (316)

Bidirectional and mediation Mendelian randomization of dietary intake and risks of gastric ulcer and gastric cancer. [PDF]

Medicine (Baltimore)
Yang L, Li L, Chen L, Liu Z, Cai J, Wang W, Yang M, He Y, Meng Z, Li F, Wang Y, Luo X.   +11 more
europepmc   +1 more source

Unraveling the Morphological and Functional Maturation Mechanisms Underlying Human Neural Development Using iPSCs‐Derived Neuronal Model

Advanced Science, EarlyView.
Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian, Yi‐Chun Ou, Zi‐Xian Zhang, Jie Cai, Si‐Qing Cai, Guo‐Gang Xing   +5 more
wiley   +1 more source

Spicy or Not? Exploring Kimchi's Spiciness Perception Across Spicy Food Tolerant and Sensitive Groups. [PDF]

J Food Sci
Chon SY, Kim MK.
europepmc   +1 more source

The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia

Advanced Science, EarlyView.
The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo, Seong‐Gook Kang, Kunlun Huang, Tao Tong   +3 more
wiley   +1 more source

Fish consumption and gastric cancer within the Stomach cancer Pooling (StoP) Project. [PDF]

Sci Rep
Franchi C, Ardoino I, Mandelli S, Patel L, Pelucchi C, Bonzi R, Camargo MC, Rabkin CS, Liao LM, Sinha R, Johnson KC, Hu J, Zhang ZF, Palli D, Ferraroni M, Negri E, Turati F, Yu GP, Lunet N, Morais S, López-Carrillo L, Tsugane S, Hidaka A, Malekzadeh R, Zaridze D, Maximovitch D, Vioque J, Gonzalez-Palacios S, Ward MH, Aragonés N, Castaño-Vinyals G, Curado MP, Dias-Neto E, Hamada GS, Hernández-Ramirez RU, Pakseresht M, Pourfarzi F, Mu L, Lagiou A, Lagiou P, López-Cervantes M, Dolci A, Boccia S, Pastorino R, Boffetta P, D'Avanzo B, La Vecchia C.   +46 more
europepmc   +1 more source

Metabolic Reprogramming of T Cells by Dual UCP2 and IL‐17 Blockade Enhances Immunity Against Pancreatic Cancer

Advanced Science, EarlyView.
This study demonstrates that dual UCP2/IL‐17 blockade reprograms T‐cell metabolism to overcome PDAC immunosuppression. Genipin‐mediated UCP2 inhibition enhances CD8⁺ T‐cell IFN‐γ via IL‐12R/STAT4/mTOR signaling and mitochondrial OXPHOS. Combined IL‐17 depletion amplifies Tc1/Th1 responses, reduces MDSCs, and prolongs survival in PDAC models ...
Chuan‐Teng Liu, Chun‐Chieh Yeh, Tsai‐Chen Wu, Chia‐Hsin Lin, Yi‐Ting Kuo, Yoichiro Iwakura, Yuan‐Ji Day, Charles Drake, Vedran Radojcic, Ying‐Chyi Song, Heng‐Hsiung Wu, Hung‐Rong Yen   +11 more
wiley   +1 more source

Mendelian Randomisation Analysis of Dietary Exposures and Potential Risks of Anxiety and Depression. [PDF]

Actas Esp Psiquiatr
Yu X, Hang R, Gan Q, Peng J.
europepmc   +1 more source

Proteogenomic Characterization Reveals Subtype‐Specific Therapeutic Potential for HER2‐Low Breast Cancer

Advanced Science, EarlyView.
Multiomic profiling of HER2‐low breast cancer identifies three proteomic subtypes with distinct therapeutic strategies: endocrine, antiangiogenic, and anti‐HER2 therapies. Genomic and lactate modification landscapes are detailed, providing insights for precise management.
Shouping Xu, Keda Yu, Lei Liu, Qin Wang, Xiaohui Wu, Yihai Chen, Guozheng Li, Xin Zhang, Bo Wei, Zitong Fu, Abiyasi Nanding, Zuxianglan Zhao, Lingbing Yang, Xingda Zhang, Jianyu Wang, Wantong Sun, Yi Hao, Zhongyi Cheng, Xiaojiang Cui, Hao Wu, Da Pang   +20 more
wiley   +1 more source

The global seafood trade, embodied nutrients, and nutritional affordability. [PDF]

Nat Commun
Liu Y, Smith MD, Abbott JK, Dietz D, Colson Leaning D, Smyth A, Yamashita T.   +6 more
europepmc   +1 more source

The Problem of the School Luncheon--Suggested Recipes and Menus, Part II [PDF]

, 1913
Gearing, Mary E., Rich, Jessie P.
core