Decellularized liver extracellular matrix scaffolds provide a platform to study dormant liver‐metastatic colorectal cancer. They induce reversible dormancy, in combination with nutrient depletion and low dose chemotherapy, through cell cycle arrest and chemotherapy resistance.
Sabrina N. VandenHeuvel +13 more
wiley +1 more source
Geometrically Tunable Scaffold‐Free Muscle Bioconstructs for Treating Volumetric Muscle Loss
Volumetric muscle loss is associated with traumatic muscle resulting in permanent functional impairment. Mold‐based, scaffold‐free, high‐density muscle tissue bioconstructs are developed in customizable geometric shapes and sizes. The transplanted rectangular solid‐shaped muscle bioconstructs improved muscle force recovery and tissue regeneration in ...
Bugra Ayan +8 more
wiley +1 more source
Climate change and health: Surveillance and action duties of the health sector [PDF]
Hernández-Flórez LJ.
europepmc +1 more source
This study presents the first human neural organoid culture model capable of rapidly exhibiting long‐distance neural network propagation, thus delivering a system to experimentally investigate large‐scale communication during normal and diseased states.
Megh Dipak Patel +6 more
wiley +1 more source
[Health research in Honduras: a decade of transformations, challenges, and sustainable institutional strengtheningPesquisa em saúde em Honduras: uma década de transformações, desafios e fortalecimento institucional sustentável]. [PDF]
Fontecha G.
europepmc +1 more source
Hybrid wrinkled topographies coordinate immune, tissue, and bacterial interactions. The surfaces promote osteointegration, tune macrophage polarization, and inhibit biofilm formation, highlighting a multifunctional strategy for next‐generation implant design.
Mohammad Asadi Tokmedash +4 more
wiley +1 more source
[Epidemiology of childhood leukemia in Mexico and Latin America: Effects of vulnerability and social justice]. [PDF]
Núñez-Enríquez JC +9 more
europepmc +1 more source
Osteoporosis from long‐term glucocorticoid (GIOP) use elevates susceptibility to fracture. This study shows GCs impair ascorbic acid (AA) metabolism in osteoblasts, collagen synthesis and extracellular matrix integrity. AA enhanced collagen biochemical and mechanical properties and restored osteoblast and endothelial function. These findings underscore
Micaila DE Curtis +19 more
wiley +1 more source
Microphysiological Systems of Lymphatics and Immune Organs
This review surveys recent progress in engineering lymphatic microenvironments and immune organoids within microphysiological systems, emphasizing innovative strategies to recreate the biochemical and biophysical complexity of native lymphatic tissues.
Ishita Jain +2 more
wiley +1 more source
[Sexual and reproductive health among adolescent girls in protection and social reintegration programs in Chile: tensions between paternalism and bodily autonomy]. [PDF]
González Aristegui D +3 more
europepmc +1 more source

