Results 31 to 40 of about 289,109 (230)

De la ética a la bioética en las ciencias de la salud

, 2020
De la Ética a la Bioética en las Ciencias de la Salud, surge desde la conceptualización de los términos ética y moral, definidos en el componente filosófico.
Myriam Bermeo de Rubio, Ivanoba Pardo Herrera, Catalina Estrada González, Anisbed Naranjo Rojas, Oscar David Rubio Bermeo, Sandra González González, Claudia Patricia Quiroga Vásquez, Mariela Sánchez Rodríguez, Freiser Eceomo Cruz Mosquera, Luis Armando Muñoz Joven, Rosa Nury Zambrano Bermeo, Yeny Mabel Lara Parra, Sonia Amparo Muñoz Fernández, Gloria Stella Lizarralde Gómez, Stephanye Carrillo González, Alba Lineth Mena Romaña, María del Carmen Martínez Cardona, Sandra Patricia Moreno Reyes, Diana Yasmín Perafán González, B. Maldonado, Luzora Mondragón Joaqui, José Eliecer Echeverri López   +21 more
semanticscholar   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Conductas de autocuidado y salud del hombre: el cáncer de próstata como ejemplo

Summa Psicológica, 1970
Resumen El presente artículo tiene como objetivo discutir los factores psicosociales relacionados al autocuidado frente al cáncer de próstata para su prevención, durante su tratamiento y en el período de post-tratamiento. El autocuidado presupone un conjunto de actividades aprendidas y orientadas para el cuidado de la salud, en las cuales el individuo
Elisa Kern De Castro, Fernanda Da Cruz Bertan   +1 more
openaire   +2 more sources

Los riesgos de los metales pesados en la salud humana y animal

, 2016
Este trabajo consiste en un estudio sobre los metales pesados y el riesgo potencial que pueden representar en la salud del hombre y los animales, incluyendo la cadena trofica.
L. Franco, P. Muñoz, Fabián Gerarado Muñoz Garcia   +2 more
semanticscholar   +1 more source

IN4MER Biomaterial Ink: A Phosphorescent Biosensing Biomaterial Ink for Multiple Analytes (Glucose, Lactate, Oxygen) Measurements and Temperature Sensing Applications

Advanced Functional Materials, EarlyView.
Multianalyte, real‐time monitoring of bioprinted scaffolds remains challenging. Phosphorescence‐lifetime–based, optically responsive microparticles are embedded in diverse printable hydrogels (κ‐carrageenan, GelMA, PEGDA) to form biomaterial inks that report oxygen, glucose, lactate, and temperature.
Waqas Saleem, David Chimene, Berkley P. White, Kaivalya A. Deo, Jeremy L. Thomas, Nithin Chidambara, Cole Mandrona, Kirsten Landsgaard, Brian Ko, Roland Kaunas, Akhilesh K. Gaharwar, Michael J. McShane   +11 more
wiley   +1 more source

Vasectomías en Colombia: ¿cómo adaptar los servicios de salud a las necesidades de los hombres?

Revista Facultad Nacional de Salud Pública, 2019
Objetivo: caracterizar sociodemográficamente a los hombres que se practican vasectomías en Colombia, para generar evidencia que oriente la adaptación de los servicios de salud con un enfoque de equidad de género a las necesidades de los hombres. Métodos:
Sandra Marcela Sánchez, Luz Janeth Forero, Juan Carlos Rivillas   +2 more
semanticscholar   +1 more source

Copper–Collagen Interactions Regulate the Mechanical and Invasive Properties of Tumor Spheroids

Advanced Healthcare Materials, EarlyView.
Ionic copper is investigated as a modulator of tumor spheroid growth and invasiveness in a 3D microfluidic glioblastoma model. Copper exposure alters metabolic activity, cytoskeletal organization, protrusion dynamics, and EMT‐related phenotypes in a dose‐ and timing‐dependent manner, revealing how copper bioavailability shapes tumor aggressiveness ...
Paula Guerrero‐López, Jose I. Garcia‐Peiro, Felipe Hornos, Jose L. Hueso, Jesus Santamaria, J. Manuel Garcia‐Aznar   +5 more
wiley   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source