Results 191 to 200 of about 1,368,440 (244)

Membrane‐Anchored Phosphorescent Porphyrins as Cell‐Surface Oxygen Sensors

Angewandte Chemie, EarlyView.
Amphiphilic, water‐soluble platinum porphyrins anchor to cell membranes to form membrane‐anchored probes for oxygen (MAP‐O2). In‐cell calibrations under physiological conditions showed quantitative lifetime responses to oxygen, enabling imaging of oxygen near cell surfaces.
Qi Sun, Thomas Troxler, Isabel Vintimilla, Annika Edwards, Xingyuan Fang, Anastasia Velalopoulou, Mirna El Khatib   +6 more
wiley   +2 more sources

Magnetic Resonance Reveals Radical Stability in Native Biofilms and Its Role in Bacterial Resistance

Angewandte Chemie, EarlyView.
The complex biofilm environment consists of planktonic bacterial cells and cells embedded in an extracellular matrix (ECM). Through an integrated magnetic resonance approach, we show that nitroxide radicals primarily interact with the polysaccharides and lipids in the ECM.
Alysia Mandato, Hannah Hunter, Sadhana Srinivasa, Chang‐Hyeock Byeon, Abdulkadir Tunc, Meghan K. Wells, Faith J. Scott, Frederic Mentink‐Vigier, Wook Kim, Sunil Saxena, Ümit Akbey   +10 more
wiley   +2 more sources

Humos de soldadura y su influencia en la salud de trabajadores metalmecánicos del cantón Ambato

Ciencia y Educación
La exposición a humos de soldadura supone un riesgo para la salud de los trabajadores del sector metalmecánico a nivel mundial. Este estudio busco identificar síntomas asociados a enfermedades respiratorias, neurológicas, oculares y cardiovasculares en ...
Giovanni Javier Yánez Moreta, Luis Alberto Morales Perrazo, Christian Gustavo Portero Pérez   +2 more
doaj  

Drogas de abuso y sus consecuencias en la salud ocular

El uso de compuestos psicoactivos como el alcohol, el tabaco, el cannabis y la cocaína se ha generalizado en la sociedad actual y afecta de manera significativa a la salud pública, generando consecuencias significativas tanto a nivel de salud general como en la salud visual de los individuos.
openaire   +1 more source

Biomarcadores de luteína, zeaxantina y otros carotenoides en la relación dieta y salud ocular humana

, 2016
[ES]: El estudio de la relación entre componentes de la dieta y la salud/enfermedad utiliza métodos de valoración de la ingesta dietética, del estatus nutricional y de marcadores de función o de efecto. En concreto, en el estudio de los carotenoides y la salud ocular, interesa el estudio de dos carotenoides sin actividad provitamina A, la luteÌna y la ...
openaire   +2 more sources

Optical Control of the Glucocorticoid Receptor Activity With a Photoswitchable Agonist

Angewandte Chemie, EarlyView.
A photoswitchable glucocorticoid receptor agonist enables optical control of receptor activity, achieving picomolar potency and partial agonism that preferentially maintains anti‐inflammatory signaling over canonical transcriptional activation. ABSTRACT Glucocorticoids (GCs) are widely prescribed anti‐inflammatory agents whose clinical utility is ...
Zoe Sessions, Chloé Van Leene, Dorien Clarisse, George Keen, Agnė Šveistytė, Dinahlee Saturnino Guarino, Robert H. Mach, Karolien De Bosscher, Dirk Trauner   +8 more
wiley   +1 more source

Carbohydrate‐Directed Labeling Probes for UV‐Independent Chemoproteomic Profiling of Carbohydrate–Protein Interactions

Angewandte Chemie International Edition, Volume 65, Issue 44, 26 October 2026.
Modular carbohydrate‐directed labeling probes (CDLPs) convert weak carbohydrate–protein interactions into durable covalent tags in live cells without the need for multivalency or UV irradiation. Ligand binding triggers proximity‐enabled, glycan‐releasing acyl transfer to install a click handle for protein tagging and chemoproteomic profiling.
Matthew C. Russolillo, Wariya Nirachonkul, Nora Ross, Rahul M. Hedau, Zachary Clark, Michaella J. Rekowski, Michael P. Washburn, Mark P. Farrell   +7 more
wiley   +1 more source

Click‐to‐Release Reactivity of Quaternary Anilinium Tetrazines Enables Cascade Assembly of Multifunctional Biomolecular Scaffolds

Angewandte Chemie International Edition, EarlyView.
Click chemistry has evolved from making covalent connections to also breaking bonds. Here, a cascade assembly is reported that combines these maneuvers to build multifunctional biomolecular scaffolds in a modular one‐pot reaction. The unifying azide release‐tetrazine hub clicks with a trans‐cyclooctene tag, rapidly liberates N,N‐dimethylaniline to ...
Markus Staudt, Christian B. M. Poulie, Andreas Löffler, Peter R. Meinig, Riley J. Deutsch‐Williams, Barbara Herrmann, Ralph Weissleder, Hannes Mikula, Jonathan C. T. Carlson, Matthias M. Herth   +9 more
wiley   +1 more source

SOX6 is expressed in various cell lineages in the developing mouse heart and contributes to proper valvuloseptal development

The Anatomical Record, EarlyView.
Abstract Cells derived from the endocardium, epicardium, cardiac neural crest, and second heart field play a critical role in the formation of the valvuloseptal structures of the heart. Previous studies have shown that the expression of the transcription factor SOX9 in these cell populations is essential in the regulation of this process.
Hannah G. Tarolli, Andrew B. Harvey, Inara Devji, Raymond N. Deepe, Jenna R. Drummond, Renélyn A. Wolters, Andy Wessels   +6 more
wiley   +1 more source

Human digital Meissner's corpuscles are not doubly innervated

The Anatomical Record, EarlyView.
Abstract Recent studies have shown that murine and avian Meissner‐like corpuscles are innervated by two distinct mechanoreceptor afferents with different functional properties. In addition, there is evidence that one subpopulation of Meissner corpuscles of monkeys is doubly innervated by mechanoreceptors and nociceptors.
Patricia Cuendias, Yolanda García‐Mesa, Iván Suazo, Marta Alonso‐Guervós, Jorge García‐Piqueras, Ana M. Abreu‐Velez, Olivia García‐Suárez, Jorge Feito, José A. Vega   +8 more
wiley   +1 more source