Results 141 to 150 of about 23,797 (214)
Pediatric Rickettsia massiliae Infection, Spain, 2023. [PDF]
Martín-Trueba J +13 more
europepmc +1 more source
Effect of Group Prenatal Care Attendance on Gestational Diabetes Mellitus and Preterm Birth
ABSTRACT Introduction Adequate prenatal care is an important tool for achieving optimal health outcomes for both mothers and their babies. A low group prenatal care (GPNC) attendance rate may influence clinical outcomes. We aimed to estimate the effect of GPNC attendance on the risk of gestational diabetes (GDM) and preterm birth (PTB). Methods This is
Roch A. Nianogo +6 more
wiley +1 more source
Gene therapy is revolutionizing treatment paradigms for haemoglobinopathies, establishing a translational framework for disorders that impact red blood cell development. In their paper, Joshi et al. describe the preclinical and early clinical landscape of gene therapies for non‐haemoglobinopathy erythroid disorders and highlight common thematic ...
Gaurav Joshi +3 more
wiley +1 more source
[Preventive and therapeutic dental care for people with various disabilities in Argentina] [PDF]
Izurieta G +3 more
europepmc +1 more source
Long‐term oncological outcomes from a prospective cohort of patients with localised prostate cancer
Objectives To report long‐term oncological outcomes for men with clinically localised prostate cancer (PCa) treated with contemporary modalities in a population‐based United States cohort. Patients and Methods The Comparative Effectiveness Analysis of Surgery and Radiation (CEASAR) study prospectively enrolled men with clinically localised PCa from ...
Avi S. Baskin +17 more
wiley +1 more source
Brain viral reservoirs were undetectable in neonatal SIV during the first 3 days post infection; antiretroviral therapy (ART) at 3 dpi prevented brain reservoir seeding and normalized metabolic function, highlighting the necessity of very early treatment to protect the developing CNS.
Li Ma +12 more
wiley +1 more source
Targeting protein–protein interactions with reversible covalent modalities: Non‐cysteine chemistries
Abstract Protein–protein interactions (PPIs) are central to diverse cellular functions, and represent a rapidly expanding class of therapeutic targets. Advancements in covalent drug design have enabled small‐molecule drugs to overcome challenges associated with engaging these targets, such as limited durations of action and difficult‐to‐drug (expansive,
Ruchira Basu, Steven Fletcher
wiley +1 more source
Cancer pain: current practice and emerging targets
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye +5 more
wiley +1 more source
Knowledge, attitude, and practices regarding climate change and its oral health effects among dental health care providers in India. A cross-sectional study. [PDF]
Preethi MV +5 more
europepmc +1 more source
Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux +26 more
wiley +1 more source

