Results 101 to 110 of about 14,367 (319)

An Agrin–YAP/TAZ Rigidity Sensing Module Drives EGFR‐Addicted Lung Tumorigenesis

Advanced Science, EarlyView.
The study identifies agrin‐EGFR mechanotransduction as a critical driver of lung adenocarcinoma which enhances EGFR signaling through an integrin‐FAK‐actomyosin dependent positive feedback on YAP/TAZ ‐TEAD in response to matrix stiffness. Targeting this oncogenic loop through combinatorial treatments inhibits lung cancer due to agrin impairment.
Reza Bayat Mokhtari, Divyaleka Sampath, Paige Eversole, Melissa Ong Yu Lin, Dmitriy A. Bosykh, Gandhi T.K. Boopathy, Aravind Sivakumar, Cheng‐Chun Wang, Ramesh Kumar, Joe Yeong Poh Sheng, Ellen Karasik, Barbara A. Foster, Han Yu, Xiang Ling, Wenjie Wu, Fengzhi Li, Zoë Weaver Ohler, Christine F. Brainson, David W. Goodrich, Wanjin Hong, Sayan Chakraborty   +20 more
wiley   +1 more source

Cell morphologies in the nervous system: Glia steal the limelight

Journal of Comparative Neurology, Volume 531, Issue 3, Page 338-343, February 2023., 2023
Diversity of digitally reconstructed glia (astrocytes, oligodendrocytes, microglia, and other types) freely available for download and reuse at NeuroMorpho.Org in terms of experimental provenance, animal species, anatomical region, cell type, tracing platform, and more.
Giorgio A. Ascoli
wiley   +1 more source

Salud y conductas relacionadas con la salud según la atracción y la conducta sexual

Gaceta Sanitaria, 2015
Objetivo: Describir la salud percibida, la salud mental y algunas conductas relacionadas con la salud según la atracción y la conducta sexual en los residentes en Barcelona en 2011. Métodos: Se analizó la salud percibida y mental, los trastornos crónicos y las conductas relacionadas con la salud, en 2675 personas de 15 a 64 años de edad teniendo en ...
Pérez, Glòria, Martí-Pastor, Marc, Gotsens, Mercè, Bartoll, Xavier, Diez, Elia, Borrell, Carme   +5 more
openaire   +5 more sources

Partition test and sexual motivation in male mice [PDF]

arXiv, 2007
Theoretical analysis of own and literature investigations of sexual motivation with the use of the partition test [Kudryavtseva, 1987, 1994] in male mice was carried out. It has been shown that appearance of a receptive female in the neighboring compartment of common cage separated by perforated transparent partition produces the enhancement of ...
arxiv  

Altered Neural Activity in the Mesoaccumbens Pathway Underlies Impaired Social Reward Processing in Shank3‐Deficient Rats

Advanced Science, EarlyView.
This study examines the effects of Shank3 mutation on the mesoaccumbens pathway using a Shank3‐deficient rat model. The findings reveal altered social reward processing in these rats, accompanied by changes in dopaminergic and GABAergic neural activity within the ventral tegmental area (VTA) and dopamine release in the nucleus accumbense (NAc ...
Marie Barbier, Keerthi Thirtamara Rajamani, Shai Netser, Shlomo Wagner, Hala Harony‐Nicolas   +4 more
wiley   +1 more source

Cuarenta años de salud sexual y (no) reproductiva

, 2023
Fil: Tiseyra, María Victoria. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Sociales.
Tiseyra, María Victoria, Pecheny, Mario Martín, Sciurano, Guido Alejo   +2 more
openaire   +1 more source

A neutral model can explain geographic patterns of sexual and asexual individuals [PDF]

arXiv, 2012
Many species reproduce both sexually and asexually producing genetically unique and clonal recruits. The relative contribution of sexual and asexual reproduction is mostly considered a consequence of natural selection, for example, disfavouring sexual propagules during invasions.
arxiv  

Identification of Tumor‐Specific Surface Proteins Enables Quantification of Extracellular Vesicle Subtypes for Early Detection of Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
Pancreatic ductal adenocarcinoma (PDAC) extracellular vesicle (EV) surface protein assay operates via a two‐step workflow – Step 1: Click chemistry‐mediated enrichment of PDAC EVs by EV Click Beads, in the presence of one of the three trans‐cyclooctene‐grafted PDAC EV‐specific antibodies; Step 2: Quantification of the enriched PDAC EVs by reverse ...
Chen Zhao, Zhili Wang, Hyoyong Kim, Hui Kong, Junseok Lee, Jacqueline Ziqian Yang, Anmin Wang, Ryan Y. Zhang, Yong Ju, Jina Kim, Bing Feng, Dejun Liu, Yating Zhang, Zhenfang Wang, Yandong Zhang, Shujing Guo, Dekang Gao, James S. Tomlinson, Renjun Pei, Jipeng Wan, Stephen J. Pandol, Myung‐Shin Sim, Sungyong You, Ding Ma, Shaohua Lu, Na Sun, Hsian‐Rong Tseng, Yazhen Zhu   +27 more
wiley   +1 more source

Early exposure to flame retardants is prospectively associated with anxiety symptoms in adolescents: A prospective birth cohort study

Depression and Anxiety, Volume 39, Issue 12, Page 780-793, December 2022., 2022
Abstract Background Anxiety disorders emerge during childhood and adolescence and are frequently preceded by subsyndromal anxiety symptoms. Environmental toxicants, including gestational polybrominated diphenyl ether (PBDE) exposure, are associated with neuropsychiatric sequelae; however, the role of PBDEs as risk factors for anxiety in adolescence is ...
Jeffrey R. Strawn, Yingying Xu, Kim M. Cecil, Jane Khoury, Mekibib Altaye, Joseph M. Braun, Bruce P. Lanphear, Andreas Sjodin, Aimin Chen, Kimberly Yolton   +9 more
wiley   +1 more source

Cuántas y dónde

Revista Internacional de Salud Materno Fetal, 2016
¿El Perú necesita más obstetras? El 05 de mayo se conmemoró a nivel global el Día Internacional de las Obstetras (Internacional Day Of The Midwife); sin embargo en nuestro País, esta fecha paso desapercibido, muy a pesar que el COP se encuentra afiliado
Mauro Huamaní Navarro
doaj