Aberrant Mitochondrial Metabolism in Alzheimer's Disease Links Energy Stress with Ferroptosis
Advanced Science, EarlyView.Alves et al. reveal how energy loss and oxidative stress, two major features of Alzheimer's disease, are connected. Mitochondria controls the flux of the antioxidant glutathione (GSH), via facilitating both its production and consumption. Energy restriction limits GSH synthesis, conferring vulnerability to cell death by ferroptosis, implicated as a ...
Francesca Alves +17 more
wiley +1 more source
Violencia sexual y problemas asociados en una muestra de usuarias de un centro de salud [PDF]
, 2001 Luciana Ramos Lira +4 more
openalex +1 more source
Factores y Consecuencias del Inicio de Vida Sexual Activa en las y los Adolescentes que acuden al centro de salud de Ciudad Darío (Clinica 1), Municipio de Matagalpa, II Semestre 2015 [PDF]
, 2016 El inicio de la vida sexual activa en la población adolescente se ha aumentado de manera evidente en los últimos años, según estudios de UNICEF (2011), aproximadamente un 11% de las mujeres y un 6% de los varones de 15 a 19 años afirmaron haber tenido ...
Aguilar Barrera, Lisseth del Carmen +1 more
core
Advanced Science, EarlyView.Macrophage GHSR‐Foxo1 axis regulates CCl4‐induced liver fibrosis by promoting inflammation and TGF‐β1‐mediated HSC activation. GHSR activates PKA‐dependent phosphorylation of Foxo1 at serine 273, promoting macrophage pro‐inflammatory polarization to enhance the production of pro‐inflammatory cytokines that damage hepatocytes, thereby inducing liver ...
Da Mi Kim +9 more
wiley +1 more source
Sex Education for my Preschooler (ages 3 to 5)? Parents’ Perceptions
Revista Electrónica Educare, 2014 This investigation was conducted as a result of the lack of studies, specifically on children’s sex education and the role that parents play in it, despite the major advances in the knowledge on sexuality and its education.
Ana Cristina Cevallos-Neira +1 more
doaj +1 more source
Reseña de Tesis de grado de Kriss N. Orozco Jara “Una mirada antropológica a un centro de atención primaria de la salud: estrategias orientadas a la población juvenil en Posadas (Misiones)” [PDF]
, 2016 A continuación se nos presenta una pormenorizada reseña del trabajo de investigación y reflexión sobre los procesos de salud-enfermedad-atención en un CAPS de la ciudad de Posadas, observando los saberes y prácticas entorno a la salud sexual y ...
Avalos, Miguel Alejandro
core +1 more source
A Subcircuit in the Suprachiasmatic Nucleus Generates Wakefulness
Advanced Science, EarlyView.This study identifies a sub‐circuit within the circadian pacemaker suprachiasmatic nucleus (SCN) that promotes arousal. This sub‐circuit is labeled by the clock output molecule mWAKE, which suppresses its excitability in a time‐dependent manner. mWAKE‐expressing cells in the SCN (SCNmWAKE cells) project to the subparaventricular zone (SPZ) to mediate ...
Qiang Liu +6 more
wiley +1 more source
[Sexual and reproductive health of young migrant women from Latin America and the Caribbean living in Chile]. [PDF]
Rev Salud Publica (Bogota), 2023 Leal-Fuentes I +2 more
europepmc +1 more source
Factores y consecuencias del inicio de Vida Sexual Activa en los y las adolescentes que asisten a la unidad de salud Molino Norte, del municipio de Matagalpa, segundo semestre 2015 [PDF]
, 2016 El presente trabajo investigativo, trata sobre los factores y las causas del Inicio de Vida Sexual Activa en los y las adolescentes del departamento de Matagalpa, con el propósito de analizar los factores y consecuencias del Inicio de Vida Sexual Activa ...
Chavarría Vargas, Alicia del Carmen +1 more
core
American Journal of Hematology, EarlyView.Key challenges in diagnosing anemia in high‐altitude populations include variability in hemoglobin (Hb) concentration, associated pathological conditions, altitude‐induced plasma volume changes, and environmental factors such as contamination and nutrition.
Ayoub Boulares +11 more
wiley +1 more source