Results 51 to 60 of about 2,081,955 (310)

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Evaluation of enzyme-linked immunoelectrotransfer blot test using purified native antigen mix from cisticercus fluid of Taenia solium for diagnosis of human cysticercosis

Revista Peruana de Medicina Experimental y Salud Pública, 2015
Objectives. Evaluate the efficiency of the enzyme-linked immunoelectrotransfer blot test (EITB) for the detection of human cysticercosis using purified native antigen mix from cysticercus fluid of Taenia solium. Material and methods.
Eduardo Ayala-Sulca, Eduardo Miranda-Ulloa   +1 more
doaj   +1 more source

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro, Mackenzie Silverman, Maeve C. Lucas, Mariam M. Yousuf, Samuel T. Otey, Stella V. Gray, Brittany Jordan, Madeline D. Kahan, Latanya D. Agurs, Michelle Van Hirtum Das, Deborah Holder, Devin King, Eileen A. Quinn, Ryan Kammeyer, Michael S. Rafii   +14 more
wiley   +1 more source

Thalamo‐Lesional Connectivity Signatures of Bilateral Tonic–Clonic Seizures in Focal Cortical Dysplasia‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie, Xiaotong Li, Venkata Sita Priyanka Illapani, Leigh N. Sepeta, Jason Schroeder, Chima O. Oluigbo, Madison M. Berl, William D. Gaillard, Nathan T. Cohen   +8 more
wiley   +1 more source

Cáncer de cuello uterino: más allá de lo que es la percepción de las mujeres de Antioquia (Colombia) y Colima (México), 2008 [PDF]

, 2009
Introducción: El cáncer de cuello uterino es un serio problema de salud pública en América Latina. Los aspectos socioculturales son relevantes para comprender las percepciones y las necesidades de las mujeres que determinan el acceso a los servicios de ...
Ma. Guadalupe Chávez M., Lucía Stella Tamayo A., Liliana María Henao F., Tamayo Acevedo, Lucía Stella, Chávez Méndez, María Guadalupe, Henao Franco, Liliana María   +5 more
core  

Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino, Lavanya Muthukumar, Evan L. Reynolds, Peter Todd, Sinem Ovunc, Sheng Chih Jin, Zitian Tang, Simone Thomas, PNRR Study Group, Ahmet Höke, Brian C. Callaghan, Sarah Berth, Vinay Chaudhry, David Cornblath, Leana Doherty, Lindsey Hayes, Hristelina Ilieva, Thomas Lloyd, Mohammad Khoshnoodi, Brett McCray, Brett Morrison, Bipasha Mukherjee‐Clavin, Lyle Ostrow, Michael Polydefkis, Ricardo Roda, Charlotte Sumner   +25 more
wiley   +1 more source

Diversidad genética y resistencia antirretroviral del virus de la inmunodeficiencia humana de tipo 1 en personal militar peruano a los 12 y a los 18 meses de seguimiento

Biomédica: revista del Instituto Nacional de Salud
Introducción. Se desconocen los factores que afectan la diversidad genética y las mutaciones de resistencia al tratamiento antirretroviral del virus de la inmunodeficiencia humana en personal militar. Objetivo.
Jonathan Guerrero, Dilan Suárez, Carlos Augusto Yabar   +2 more
doaj   +1 more source

Norma técnica de salud de planificación familiar [PDF]

, 2017
RESUMEN En este contexto, el Ministerio de Salud, comprometido en la mejora de la salud sexual y reproductiva de la población, viene desarrollando diversas acciones para mejorar el acceso de la población a los diferentes métodos anticonceptivos siendo
Perú. Ministerio de Salud
core  

Factors Associated With the Rising Trend in Self‐Reported Cognitive Disability Among U.S. Adults Aged 18–39 From 2013–2024

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Building on our prior Behavioral Risk Factor Surveillance System analysis identifying adults aged 18–39 as the primary driver of the national increase in self‐reported cognitive disability, we examined factors associated with this rise using 2013–2024 U.S. BRFSS data. Methods We analyzed U.S.
Adam de Havenon, Ka‐Ho Wong, Mirriam Mananah, Christopher D. Anderson, Ada Fenick, Amy Arnsten, Arman Fesharaki‐Zadeh, James C. McPartland, Mary L. Adams, Kevin N. Sheth   +9 more
wiley   +1 more source

La necesidad de apoyo psicoemocional a los hombres durante la paternidad. Estudio cualitativo

Atención Primaria
Resumen: Objetivo: Explorar las experiencias de los padres primerizos en función de su participación o no en los grupos de preparación a la paternidad en un entorno rural. Diseño: Estudio cualitativo con enfoque fenomenológico y perspectiva hermenéutica.
Ariadna Cirera Autet, Ester Muñoz-Sellés, María Monreal Barba, Judit Tarrés Rovira   +3 more
doaj   +1 more source