Results 181 to 190 of about 499,794 (257)

Prevalence and Clinicoradiopathological Characterization of H3 K27-Altered Diffuse Midline Gliomas in Adults-A Retrospective Observational Study. [PDF]

Pathophysiology
Babarczy K, Radics BL, Kiss L, Graczer A, Nagy B, Dosa S, Kelemen G, Balazsfi M, Barzo P, Voros A, Klivenyi P, Szalardy L.   +11 more
europepmc   +1 more source

UNCITRAL Draft Convention on Carriage of Goods by Sea, Part 2 [PDF]

, 1975
Sweeney, Joseph
core   +4 more sources

Improved Systemic Immunochemotherapy Employing an Oxaliplatin‐TLR7/8 Agonist Prodrug Strategy

Advanced Science, EarlyView.
A platinum(IV) prodrug is developed to systemically deliver the TLR7/8 agonist gardiquimod. Tumor‐targeting is mediated by an albumin‐binding maleimide, which limits premature complex activation. Ox‐Gardi‐Mal accumulates specifically in the tumor, where it activates the immune system.
Michael Gutmann, Martijn Dijkstra, Philipp Salomon, Jamie Cowles, Anja Federa, Dina Baier, Carola Jaunecker, Iemima Semerean, Venla Karvonen, Christine Pirker, Maria Sibilia, Dietmar Herndler‐Brandstetter, Petra Heffeter, Bernhard K. Keppler, Christian R. Kowol, Walter Berger   +15 more
wiley   +1 more source

Long-Term Outcomes of Consolidative Proton Therapy for Pediatric Classical Hodgkin Lymphoma. [PDF]

Int J Part Ther
Martir-Vargas D, Indelicato DJ, Bechtel A, Bansal M, Milner J, Dean JB, Morris CG, Mendenhall NP, Mailhot Vega RB.   +8 more
europepmc   +1 more source

Mid-America Regional Bargaining Association, Fox Valley General Contractors Association (Building) and Laborers International Union of North America (LIUNA), Construction & General Laborers District Council of Chicago & Vicinity, Local 1035, 582, 149 (2001) [PDF]

, 2001

core   +1 more source

Functional Analysis of Ligand‐Gated Chloride Channels in a Cnidarian Sheds Light on the Evolution of Inhibitory Signaling

Advanced Science, EarlyView.
We uncover a large variety of putative inhibitory ligand‐gated ion channels (LGICs) in the phylum Cnidaria, the sister group to all bilaterian animals. Phylogenetic analysis suggests a complex evolutionary history of inhibitory LGICs with diverse neurotransmitter ligands.
Abhilasha Ojha, Linda Kloss, Juan D. Montenegro, Simone Albani, Audrey Ortega‐Ramírez, Mihaela Raycheva, Sylvia Joussen, Sabrina Kaul, Michèle Bachmann, Lisa Huf, Günther Schmalzing, Alison G. Cole, Ulrich Technau, Stefan Gründer   +13 more
wiley   +1 more source

IGH::FENDRR and specific KRAS mutations define a novel B-ALL molecular subtype with poor chemotherapy response. [PDF]

Blood
Bendig S, Hartmann AM, Wessels W, Beder T, Kim R, Passet M, Gao Q, Wolgast N, Horns JM, Alves Santos L, Iben K, Steffen FD, Cantoni L, Kehden B, Chitadze G, Künstner A, Busch H, Bornhauser B, Bourquin JP, Leguay TT, Boissel N, Gökbuget N, Iacobucci I, Mullighan CG, Clappier E, Baldus CD, Brüggemann M, Bastian L.   +27 more
europepmc   +1 more source

An Open‐Source Pipeline for Calcium Imaging and All‐Optical Physiology in Human Stem Cell‐Derived Neurons

Advanced Science, EarlyView.
This work introduces an open‐source all‐optical platform for functional phenotyping of human stem cell‐derived neurons. The system integrates optogenetics, calcium imaging, automated acquisition, and analysis to resolve single‐cell and network activity, enabling longitudinal measurements, disease modeling, and pharmacological screening in preclinical ...
Wardiya Afshar‐Saber, Federico M. Gasparoli, Ziqin Yang, Nicole A. Teaney, Rachel Hobson, Lahin Lalani, Gayathri Srinivasan, Dosh Whye, Ranit Karmakar, Elizabeth D. Buttermore, Kellen D. Winden, Cidi Chen, Mustafa Sahin   +12 more
wiley   +1 more source

Ipilimumab with and without nivolumab in patients with classic Hodgkin lymphoma with progression after PD-1 blockade. [PDF]

Blood Neoplasia
Merryman RW, Kline J, Redd RA, Olszewski H, Welsh E, Pfaff K, Lee H, McDonough M, Ahn IE, Brown JR, Crombie JL, Davids MS, Fisher DC, Jacobsen ED, Jacobson CA, Kim AI, Odejide OO, Parry EM, Ryan CE, Shipp MA, Armand P, Rodig S, Abramson JS, LaCasce AS.   +23 more
europepmc   +1 more source

Targeting Peptostreptococcus anaerobius with an Iron‐Based Nanozyme Reverses Ferroptosis Resistance and Enhances Antitumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao, Jun Wang, Hanwenchen Wang, Xiang Sun, Fang Fang, Shiying Li, Jianping Liu, Changrong Shi, Pengyuan Qi, Jianhua Zou, Xiaoyuan Chen, Kailin Cai   +11 more
wiley   +1 more source