Results 141 to 150 of about 756 (176)

Intranasal Delivery of Gallium–Quercetin Nanoparticles for Multi‐Target Ferroptosis Inhibition in Parkinson's Disease

Advanced Science, EarlyView.
Leveraging the chemical similarity between Ga3+ and Fe3+ as well as the antioxidant properties of quercetin, gallium–quercetin nanoparticles (GQNPs) were prepared to integrate iron homeostasis regulation, oxidative stress suppression, and mitochondrial protection for multi‐target ferroptosis inhibition in Parkinson's Disease.
Keyang Xu, Dandan Kou, Xiao Xiao, Bingbing Bai, Caide Liu, Mengyao Wu, Yadan Shi, Mengdan Xu, Xiaoyi Cao, Haodi Qi, Shuhua Wu, Jianfeng Zeng, Mingyuan Gao   +12 more
wiley   +1 more source

Generative machine learning produces kinetic models that accurately characterize intracellular metabolic states. [PDF]

Nat Catal
Choudhury S, Narayanan B, Moret M, Hatzimanikatis V, Miskovic L.   +4 more
europepmc   +1 more source

Advancing Energy Efficiency in Smart Windows via Dual‐Responsive Electro‐Thermochromism

Advanced Science, EarlyView.
A durable and stable quasi‐solid‐state electro‐thermal dual‐responsive photothermal regulation device has been employed in advanced energy‐efficient smart windows. The devised device not only incorporates a thermochromic hydrogel characterized by high ionic conductivity, high optical transmittance, and a low LCST, but also comprises an electrochromic ...
Tongyu Chen, Bing Xu, Guolong Zhou, Wenting Wu, Bingkun Huang, Xiaohui Tang, William W. Yu, Pooi See Lee, Wu Zhang, Zhongyang Wang, Jingwei Chen   +10 more
wiley   +1 more source

Transition From a High-Sugar and Butter to a Standard Diet Leads to Cecal Dysbiosis, Disrupts Intestinal Homeostasis, and Favors Increased Ethanol Consumption and Preference. [PDF]

FASEB J
Júnior REM, Mendes MV, Amormino MS, Randuineau G, Le Boulenger C, Guérin S, Romé V, Boudry G, Brunialti-Godard AL.   +8 more
europepmc   +1 more source

An Innervated Human Skin Equivalent that Electrically Encodes Mechanical and Thermal Stimuli

Advanced Science, EarlyView.
An innervated human skin equivalent is integrated with high‐density microelectrode arrays to reveal how engineered free nerve ending–like structures translate touch and temperature into electrical codes. Mechanical indentation and thermal stimulation engage the engineered somatosensory circuitry and evoke distinct firing and waveform signatures ...
Daniele Bellantoni, Costantino Casale, Marika Sperduti, Nevio L. Tagliamonte, Giorgia Imparato, Loredana Zollo, Paolo A. Netti   +6 more
wiley   +1 more source

Tetrahydrobiopterin and Autism Spectrum Disorder: A Systematic Review of a Promising Therapeutic Pathway. [PDF]

Brain Sci
Filho CC, Melfior L, Ramos SL, Pizi MSO, Taruhn LF, Muller ME, Nunes TK, Schmitt LO, Gaspar JM, de Oliveira MA, Tassinari G, Cruz L, Latini A.   +12 more
europepmc   +1 more source

Liquid Gallium Nanozyme Coatings Enable Sustained Nitric Oxide Generation With Antioxidant and Anti‐Inflammatory Functions

Advanced Science, EarlyView.
Liquid gallium (Ga) acts as a catalytic center for nitric oxide (NO) generation within a tannic acid–zirconium metal–phenolic network coating. Stabilized Ga nanoparticles catalyze S‐nitrosothiol decomposition through surface electron transfer, enabling controlled NO production, enhancing endothelial biocompatibility, and providing antioxidant and anti ...
Franco Centurion, Kang Lin, Shu Geng, Siti Nur Asyura Adzlan, Qingqing Fan, Federico Mazur, Ravindra Kokate, Priyank Kumar, Christina Cortez‐Jugo, Frank Caruso, Rona Chandrawati   +10 more
wiley   +1 more source

Novel Lipophagy Inducers as Potential Therapeutics for Lipid Metabolism Disorders. [PDF]

ACS Chem Biol
Njeim R, Awada B, Donow H, Gye H, Foster C, Kelly C, Molina J, Merscher S, Giulianotti M, Fornoni A, Al-Ali H.   +10 more
europepmc   +1 more source

Case Report: Molecular diagnostics and clinical courses of two adult spinal pilocytic astrocytoma long-term survivors with GTF2I::BRAF fusion. [PDF]

Front Oncol
Argao L, Zerk PE, Lu HC, Abdullaev Z, Quezado M, Cassidy ML, Mclver B, Choi A, Panzer M, Tweneboah-Koduah R, Polskin L, Penas-Prado M, Park P, Clarke N, Aldape K, Mandel J, Ozer BH.   +16 more
europepmc   +1 more source