Results 71 to 80 of about 756 (176)

Deep brain stimulation for clozapine-resistant schizophrenia: a systematic review of target-specific outcomes and stereotactic technical considerations. [PDF]

Neurosurg Rev
Armando AR, Fahmi A, Subianto H, Turchan A, Wang W, Peng Y, Kamaruddin MF, Syaharani R, Zamzam RR, Maulina N.   +9 more
europepmc   +1 more source

An Integrative Strategy Delineates Modular Metabolic Remodeling and Potential Therapeutic Targets Across Metabolic Diseases

Advanced Science, EarlyView.
An integrative single‐cell atlas across multiple metabolic diseases reveals coordinated metabolic modules and disease‐shared versus disease‐specific pathway activities. By systematically comparing scoring strategies, a robust RankAve framework is established. Coupled with network analysis and drug‐target prediction, this resource uncovers cross‐disease
Kuan Yang, Congxue Hu, Hang Zhao, Xiao Peng, Yiming Yan, Jiasi Wang, Wenqi Jiang, Depeng Mu, Yan Cao, Xia Li, Yunpeng Zhang   +10 more
wiley   +1 more source

Ten common misconceptions about Galaxy (and why they are wrong!). [PDF]

PLoS Comput Biol
Bacon WA, Batut B, Srikakulam SK, Zierep P, Bretaudeau A, Grüning B, Le Corguillé G, Hecht H, Davis JY, Hotz HR, Serrano-Solano B.   +10 more
europepmc   +1 more source

Nano‐Backpack Engineered Probiotics with Reactive Oxygen Species–Responsive Tungsten Release for Synergistic Therapy of Inflammatory Bowel Disease

Advanced Science, EarlyView.
An integrated probiotic system is engineered to execute a programmed therapeutic cascade against inflammatory bowel disease. Upon pathological signals, the system sequentially performs ROS scavenging, tungsten release, and selective pathogen suppression, thereby breaking the oxidative stress–dysbiosis cycle to remodel gut microbiota and reinforce ...
Yang Yang, Liucan Wang, Guoqing Chen, Yuanling Zhang, Jiarui Shi, Wenzhe Fan, Min Yu, Jixi Zhang, Hua Yang   +8 more
wiley   +1 more source

Screening, sorting, and the feedback cycles that imperil peer review. [PDF]

PLoS Biol
Bergstrom CT, Gross K.
europepmc   +1 more source

A Hydrogen Sulfide–Releasing Dynamic Hydrogel Modulates Coordinated Neurovascular, Immune, and Angiogenic Responses for Scar‐Suppressed Diabetic Wound Repair

Advanced Science, EarlyView.
ROS‐Responsive H2S Hydrogel (HAPPF) Coordinated Regeneration for High‐Quality Diabetic Wound Repair.A self‐regulating dynamic hydrogel is developed to deliver a fluorogenic H2S donor in response to excessive ROS. Released H2S acts as a master regulator to resolve chronic inflammation (M2 polarization), restore VEGF‐driven angiogenesis, and rebalance ...
Xuyang Ning, Ziqiang Zhou, Bangming Li, Hong Lu, Haoyang Wen, Zhoulong Huang, Gang Li, Ping Hu   +7 more
wiley   +1 more source

Designing research interfaces for non-human minds: a biocentric design approach for animal cognition research. [PDF]

Anim Cogn
Roth TS, Hirskyj-Douglas I, Perea-García JO.   +2 more
europepmc   +1 more source

High Tree Species Diversity Promotes Thermal Enhancement Response of Microbial Carbon Use Efficiency

Advanced Science, EarlyView.
ABSTRACT Predicting soil carbon dynamics under warming is constrained by limited understanding of microbial thermal adaptation, particularly whether microbial carbon use efficiency (CUE) can adapt to warming and how plant diversity modulates this response. Using soils from a natural tree species diversity gradient in a subtropical forest, we combined a
Pengpeng Duan, Changqing Ye, Xinyi Yang, Chaoqun Wang, Wolfgang Wanek, Jian‐sheng Ye, Hongzhao Yuan, Hu Du, Kongcao Xiao, Xunyang He, Kelin Wang, Dejun Li   +11 more
wiley   +1 more source

Cabergoline-Induced Gambling Causing Increased Adrenal Crisis Episodes. [PDF]

JCEM Case Rep
Martinez-Gil M, Aghel S, Tshimbombu TN, Yuen KCJ.   +3 more
europepmc   +1 more source

Circadian transcription factor NPAS2 and the NAD⁺ -dependent deacetylase SIRT1 interact in the mouse nucleus accumbens and regulate reward. [PDF]

Eur J Neurosci, 2022
Becker-Krail DD, Parekh PK, Ketchesin KD, Yamaguchi S, Yoshino J, Hildebrand MA, Dunham B, Ganapathiraju MK, Logan RW, McClung CA.   +9 more
europepmc   +1 more source