Results 221 to 230 of about 371,970 (361)

Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy   +7 more
wiley   +1 more source

Motion Mitigation Techniques for Abdominal and Cardiac MR Imaging

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT MRI of the heart and abdominal organs provides unparalleled soft tissue contrast and quantitative biomarkers, yet remains highly susceptible to physiological motion. Contractions of the myocardium, respiratory excursions, peristalsis, vascular pulsatility, and unpredictable bulk patient movement generate artifacts that impair image quality ...
Eric M. Schrauben   +3 more
wiley   +1 more source

Perioperative utilization of JAK inhibitors in Perianal Fistulizing Crohn's disease

open access: yesJPGN Reports, EarlyView.
Abstract With the recent approval of small molecule drugs such as upadacitinib in adult inflammatory bowel disease (IBD), their utilization is becoming more common; however, there is limited data on perioperative risks or optimal timing of cessation and resumption to mitigate flares. Current recommendations suggest holding these medications for 14 days
Alexander Lyons   +2 more
wiley   +1 more source

Ruxolitinib and vedolizumab salvage therapy in the setting of cytomegalovirus colitis for a patient with newly diagnosed very early onset inflammatory bowel disease

open access: yesJPGN Reports, EarlyView.
Abstract Acute severe ulcerative colitis increases the risk for cytomegalovirus (CMV) infection, particularly with the use of immunocompromising medications. We report a case of a 4‐year‐old with newly diagnosed very early onset inflammatory bowel disease presenting with acute severe colitis refractory to both corticosteroids and infliximab, whose ...
Alison Laxer   +3 more
wiley   +1 more source

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