Results 161 to 170 of about 11,678 (308)

Senolytic Therapy as a Preventive Strategy for Spine Degeneration and Pain

Advanced Science, EarlyView.
Cellular senescence promotes inflammation, tissue degeneration, and chronic back pain. In sparc‐null mice, early oral administration of the senolytic agents o‐vanillin and RG‐7112 reduced senescent cell burden and pro‐inflammatory SASP signaling across intervertebral discs, endplates, vertebral bone, and spinal cord.
Saber Ghazizadeh, Hosni Cherif, Matthew Mannarino, Juiena Sagir, Magali Millecamps, Jean A. Ouellet, Laura S. Stone, Lisbet Haglund   +7 more
wiley   +1 more source

EVALUATION OF THE RADIOISOTOPIC SYNOVECTOMY PROTOCOL IN PATIENTS WITH HEMOPHILIA. [PDF]

Acta Ortop Bras
Martins MDS, Ricciardi JBDS, Santos AO, Ozelo MC, Pagnano RG, Sakuma ETI.   +5 more
europepmc   +1 more source

ANKS1B in the Nucleus Accumbens Controls Escalated Cocaine Self‐Administration via Regulating CBP‐FoxO3 Complex

Advanced Science, EarlyView.
ANKS1B in the nucleus accumbens plays a critical role in the transition from controlled to escalated cocaine intake. Mechanistically, ANKS1B interacts with CBP to epigenetically suppress FoxO3 through H3K27 acetylation. The ANKS1B‐CBP‐FoxO3 signaling cascade presents a novel theraputic target for the treatment of cocaine addiction.
Liping Yang, Xiaoxuan Wu, Xuan Chen, Chao Peng, Zihang Li, Shumin Gao, Shiqiu Meng, Jing Dong, Dong Wu, Liying Lv, Ying Han, Yanxue Xue, Lin Lu, Jie Shi, Jianfeng Liu, Yan Sun   +15 more
wiley   +1 more source

Localization of samarium-153 EDTMP in normal bone

, 1991
Typescript (photocopy).The objective of this study was to determine the area and method of localization of samarium-153-ethylenediaminetetramethylene phosphonic acid (153Sm-EDTMP) in normal bone so that this information might.be used to refine the ...
Chambers, Mark Douglas
core  

Growth and EPR properties of KSm(WO4)2 and KEr(WO4)2 single crystals

Open Physics, 2012
Leniec Grzegorz, Skibiński Tomasz, Kaczmarek Slawomir, Iwanowski Przemyslaw, Berkowski Marek   +4 more
doaj   +1 more source

Pressure-Induced Reduction of Dicyanamide by Samarium(II) in a Coordination Polymer. [PDF]

Inorg Chem
Wineinger HB, Hines TW, Mendoza KN, Rajeshkumar T, Beck NB, Maron L, Sperling JM, Albrecht TE.   +7 more
europepmc   +1 more source

Tunable Negative Thermal Expansion in Fe/Cr‐Substituted Nd2Co17 Compounds via Magnetoelastic Coupling

Advanced Science, EarlyView.
This study achieves anisotropic thermal expansion tuning in Nd2(Co1‐xFex)17‐yCry compounds via a magnetoelastic strategy. Variable‐temperature synchrotron X‐ray diffraction reveals that increased Fe content induces switchable lattice responses. Compositional control reduces the volume expansion coefficient αV by 20% (x═0.7) and modulates TC (442–625 K),
Jiayuan Li, Chenfei Qv, Haoran Tu, Qinfen Gu, Wayne D. Hutchison, Stewart J. Campbell, Zhenxiang Cheng, Wenquan Wang, Jianli Wang   +8 more
wiley   +1 more source

Development of samarium-doped microspheres for internal radiotherapy treatment of bone metastases

Internal radiotherapy, also known as brachytherapy, and or selective internal radiotherapy (SIRT), delivers radioactive sources inside the body, near to or into malignant tumours, which may be particularly effective when malignancies are not responding ...
Arjuna, Andi
core   +1 more source

From Electrolyte to Alloys: Electrodeposition of Rare Earth Element-Based Thin Films-State of the Art. [PDF]

Materials (Basel)
Rudnik E.
europepmc   +1 more source

Disruption of the SNRPF–DDX24–E2F4 Feedback Loop Uncouples Splicing and Transcriptional Regulation to Suppress Ovarian Cancer Progression

Advanced Science, EarlyView.
This study identifies SNRPF as a critical oncogenic driver in ovarian cancer. By regulating a self‐sustaining SNRPF–DDX24–E2F4 feedback loop through intron retention and nonsense‐mediated decay, SNRPF couples RNA splicing with transcriptional regulation to promote tumor progression.
Yingwei Li, Zhongshao Chen, Qianqian Gao, Yuehan Gao, Ning Yang   +4 more
wiley   +1 more source