Results 131 to 140 of about 6,949,480 (286)

Data‐Driven SuStaIn Model of Disability Progression in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether ordinal Subtype and Stage Inference (SuStaIn) applied to routine ALSFRS‐R item scores can identify reproducible disability progression patterns in amyotrophic lateral sclerosis (ALS) and provide clinically meaningful staging.
Giammarco Milella   +5 more
wiley   +1 more source

Boundary‐Dependent Sleep–Wake Dysregulation in Idiopathic Hypersomnia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Idiopathic hypersomnia (IH) presents with excessive daytime sleepiness (EDS) despite apparently preserved nocturnal sleep, challenging traditional models of hypersomnolence based on sleep loss or fragmentation. We aimed to test the hypothesis that EDS in IH reflects excessive stabilization of the sleep state, consistent with ...
Samantha Mombelli   +13 more
wiley   +1 more source

Same-Sex Marriage

open access: yes
Cover -- Half Title -- Title -- Copyright -- Contents -- Foreword -- Introduction -- Chapter 1: How Did Same-Sex Marriage Become Legal in the United States?
Thompson, Tamara.
core  

Association Between Neurofilament Light Chain and Real‐World Ambulatory Function in Progressive MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurofilament light chain (NfL) is a biomarker of neuroaxonal injury in multiple sclerosis (MS), yet associations with functional outcomes remain unclear. Longitudinal associations between serum NfL (sNfL) and daily step count (STEPS) from wearable devices were assessed in a large international progressive MS cohort.
Gabby B. Joseph   +5 more
wiley   +1 more source

Constitutional principle of equality and legal regulation of gay marriages

open access: yesZbornik Radova Pravnog Fakulteta u Splitu, 2013
Modern democratic legal organisation holds the rights of the individual or person as its fundamental value. However, the significance, main idea and aim of such organisation is the creation of an adequate social environment for the complete and free ...
Sanja Barić, Sanja Vincan
doaj  

Clinical Impact of MGMT Promoter Methylation in IDH‐Mutant Gliomas: Influence of Threshold Selection and Clinical Confounding

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background The clinical relevance of MGMT promoter methylation in IDH‐mutant gliomas remains controversial in the era of molecular classification. We aimed to systematically evaluate its clinical relevance by integrating quantitative assessment, cutoff exploration, and adjustment for clinical confounding.
Haihui Jiang   +7 more
wiley   +1 more source

Constitutional Courts and Same-Sex Family Rights: The Case of Lithuania within the Eastern and Central European Context

open access: yesBaltic Journal of Law & Politics
In recent decades, Europe has witnessed considerable advancement in the legal recognition of same-sex couples’ family relationships; nevertheless, Lithuania remains among the most conservative member states of the EU in addressing this matter.
Pūraitė-Andrikienė Dovilė
doaj   +1 more source

Same-sex intimate partner homicide in Australia [PDF]

open access: yes, 2014
This study uses data from the National Homicide Monitoring Program within a context of national and international research to describe what is known about the trends and key characteristics of same-sex intimate partner homicide in Australia.
Alexandra Gannoni, Tracy Cussen
core  

Cerebrospinal Fluid Over Plasma Links Analytes to Cognitive Decline in Older Adults at Risk for Alzheimer's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...
Jagan A. Pillai   +13 more
wiley   +1 more source

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