Results 41 to 50 of about 11,621,791 (252)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

A Queer Series of Events: A Comparative Examination of Same-Sex Marriage Legalization [PDF]

open access: yes, 2022
As of 2020, same-sex marriage has been legalized at the national level in 28 countries. This dissertation examines the factors that make legalization of same-sex marriage (same-sex marriage) more likely. Using quantitative analysis and a customized index,
Shea, Michael
core   +1 more source

Homo-afetividade e direitos humanos Homoaffectivity and human rights

open access: yesRevista Estudos Feministas, 2006
A união civil entre pessoas do mesmo sexo é analisada neste ensaio discutindo-se as raízes do preconceito anti-homossexual e a luta pela cidadania de Gays, Lésbicas e Transgêneros no Brasil, elencando-se as diferentes manifestações da homofobia em nosso ...
Luis Mott
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Same-sex intimate partner homicide in Australia [PDF]

open access: yes, 2014
This study uses data from the National Homicide Monitoring Program within a context of national and international research to describe what is known about the trends and key characteristics of same-sex intimate partner homicide in Australia.
Alexandra Gannoni, Tracy Cussen
core  

The Identity Turn in European Citizenship Law

open access: yesEuropean Papers
(Series Information) European Papers - A Journal on Law and Integration, 2026 11(2), 1181–1203 | Article | (Table of Contents) 1. Introduction – 2. The jurisprudential context – 2.1. Citizenship from solidarity to identity – 2.2. Values and competence in
Gareth Davies
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Same-sex marriage: issues for the 44th Parliament [PDF]

open access: yes, 2015
Australia has achieved a high degree of equality between the treatment of same-sex and heterosexual relationships with marriage remaining the one significant area of difference.
Mary Anne Neilsen
core  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

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