Results 161 to 170 of about 14,737,167 (364)

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

open access: yesMolecular Oncology, EarlyView.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa   +13 more
wiley   +1 more source

You\u27re My All In All Sweet Dora Bell [PDF]

open access: yes, 1908
https://digitalcommons.library.umaine.edu/mmb-me/1292/thumbnail ...
Guild, Jennie Sample
core   +1 more source

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu   +7 more
wiley   +1 more source

The Effect of Electronic Nicotine Delivery Systems on the Vocal Folds [PDF]

open access: yes, 2019
Electronic Nicotine Delivery Systems (ENDS) are non-combustible tobacco products that are rapidly gaining in popularity worldwide. ENDS are marketed as safer alternatives to cigarettes; however, very little research is available to support or deny these ...
Sample, Hilary Gayle
core   +1 more source

KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells

open access: yesMolecular Oncology, EarlyView.
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock   +10 more
wiley   +1 more source

Reliable Imputed-Sample Assisted Vertical Federated Learning [PDF]

open access: yesarXiv
Vertical Federated Learning (VFL) is a well-known FL variant that enables multiple parties to collaboratively train a model without sharing their raw data. Existing VFL approaches focus on overlapping samples among different parties, while their performance is constrained by the limited number of these samples, leaving numerous non-overlapping samples ...
arxiv  

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