A potential tumor suppressor role of PLK2 in glioblastoma
PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia+5 more
wiley +1 more source
SAMPLE: An R Package to Estimate Sampling Effort for Species' Occurrence Rates. [PDF]
Bravo H+2 more
europepmc +1 more source
Identification of inhibitors of the Salmonella FraB deglycase, a drug target
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law+6 more
wiley +1 more source
Effect of Crosslinking Temperature on the Insulation Performance of XLPE Secondary Crosslinking Insulation Interface Layer. [PDF]
Hu M+7 more
europepmc +1 more source
Sample size recalculation based on the overall success rate in a randomized test-treatment trial with restricting randomization to discordant pairs. [PDF]
Elzner C, Pepić A, Gerke O, Zapf A.
europepmc +1 more source
High-Precision Oxygen-Isotope Analysis of Iron (Oxyhydr)oxides Using High-Temperature Conversion Isotope Ratio Mass Spectrometry. [PDF]
Galili N+6 more
europepmc +1 more source
Addressing overfitting bias due to sample overlap in polygenic risk scoring. [PDF]
Jeong S+13 more
europepmc +1 more source
A biosensor-integrated filtration device for nanoparticle isolation and label-free imaging.
Liu L+8 more
europepmc +1 more source