Results 81 to 90 of about 14,737,167 (364)

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

Un model de regenerare urbană: o Uzină de Apă sau un Centru de Arhitectură, Cultură Urbană şi Peisaj?

open access: yesSociologie Românească, 2012
The reconversion of industrial buildings has become a common practice in urban landscapes, due to cultural changes that have occurred in post-industrial societies.
Alma Procopianu, Iosif Ciprian Pantea
doaj  

The Work Sample Verification and the Calculation of the Statistical, Mathematical and Economical Probability for the Risks of the Direct Procurement [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2017
Each organization has among its multiple secondary endpoints subordinated to a centralobjective that one of avoiding the contingencies. The direct procurement is carried out on themarket in SEAP (Electronic System of Public Procurement), and a performing
Lazăr Cristiana Daniela   +2 more
doaj  

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

open access: yesFEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti   +3 more
wiley   +1 more source

Differential Privacy By Sampling [PDF]

open access: yesarXiv, 2017
In this paper we present the Sampling Privacy mechanism for privately releasing personal data. Sampling Privacy is a sampling based privacy mechanism that satisfies differential privacy.
arxiv  

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

open access: yesMolecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens   +8 more
wiley   +1 more source

Shattering stereotypes: aging adults aren't naturally unhappy [PDF]

open access: yes, 1998
Journal ArticleHealthy older adults ramain engaged and interested in life. Just because they're aging doesn't mean they lose interest in life. "In this culture, we have a perception of what it's like to grow old: life isn't a whole lot of fun" We have an
Sample, Susan
core  

Assessing Academic Advisement Preferences Among Master’s Students: A Modification of the Prescriptive/Developmental Preference Scale [PDF]

open access: yes, 2023
Academic advisement plays a significant role in enrollment retention and degree attainment. Little is known, however, about what master’s students want and need from their advisement experience, as most research on advisement preferences has focused on ...
Sample, Marian Gina
core   +1 more source

Gradient-based Sampling: An Adaptive Importance Sampling for Least-squares [PDF]

open access: yes30th Conference on Neural Information Processing Systems (NIPS 2016), Barcelona, Spain, 2018
In modern data analysis, random sampling is an efficient and widely-used strategy to overcome the computational difficulties brought by large sample size. In previous studies, researchers conducted random sampling which is according to the input data but independent on the response variable, however the response variable may also be informative for ...
arxiv  

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Home - About - Disclaimer - Privacy