Results 201 to 210 of about 1,264,517 (335)

scIRT: Imputation and Dimensionality Reduction for Single-Cell RNA-Seq Data by Combining NMF with SMOTE. [PDF]

Int J Mol Sci
Mou Y, Li S, Ji G.
europepmc   +1 more source

Nested Sampling for Exploring Lennard-Jones Clusters [PDF]

Lune Maillard, Fabio Finocchi, César Godinho, M. Trassinelli   +3 more
openalex   +1 more source

Consumption of food in the EU by the degree of urbanization: data visualization and cluster analysis of the EU sample

, 2020
Lenka Maličká
openalex   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Benchmarking UMI clustering tools for accurate detection of low-frequency variants from deep sequencing. [PDF]

Sci Rep
Pu D, Li J, Li J, Qin S, Qiu X, Wang Z, Shu K.   +6 more
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

scSCCNIA: similarity matrix based contrastive clustering with neighbor information aggregation for single-cell RNA sequencing data. [PDF]

Brief Bioinform
Wang J, Xia J, Su Y, Zheng CH.
europepmc   +1 more source

Cluster over individual randomization: are study design choices appropriately justified? Review of a random sample of trials

, 2020
Monica Taljaard, Cory E. Goldstein, Bruno Giraudeau, Stuart G. Nicholls, Kelly Carroll, Spencer Phillips Hey, Jamie Brehaut, Vipul Jairath, Alex John London, Sandra Eldridge, Jeremy Grimshaw, Dean Fergusson, Charles Weijer   +12 more
openalex   +2 more sources

The clustering of galaxies in the SDSS-III Baryon Oscillation Spectroscopic Survey: mock galaxy catalogues for the low-redshift sample [PDF]

, 2014
Marc Manera, Lado Samushia, Rita Tojeiro, Cullan Howlett, Ashley J. Ross, Will J. Percival, Héctor Gil-Marín, Joel R. Brownstein, A. Burden, Francesco Montesano   +9 more
openalex   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source