Results 51 to 60 of about 1,264,517 (335)

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Weighted Fuzzy Clustering Algorithm Based on Dynamic Interval

open access: yesJisuanji kexue yu tansuo, 2020
Clustering is widely used in data mining and data analysis, and a great many of troubles have been caused by incomplete data in clustering. Aiming at the inaccurate problem of filling missing attributes with estimation method in incomplete data ...
LUO Hao, WANG Yanjie, NIU Minghang, QIU Cunyue, ZHANG Li
doaj   +1 more source

Constraining the HI-Halo Mass Relation From Galaxy Clustering

open access: yes, 2017
We study the dependence of galaxy clustering on atomic gas mass using a sample of $\sim$16,000 galaxies with redshift in the range of $0 ...
Guo, Hong   +7 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Sample Latent Feature-Associated Low-Rank Subspace Clustering for Hyperspectral Band Selection

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
In recent years, subspace clustering has become increasingly popular and achieved great success in band selection (BS) of hyperspectral imagery. However, current subspace clustering approaches are mostly insufficient in capturing the fine spatial ...
Yujie Guo   +4 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Constraints on Assembly Bias from Galaxy Clustering

open access: yes, 2016
We constrain the newly-introduced decorated Halo Occupation Distribution (HOD) model using SDSS DR7 measurements of projected galaxy clustering or r-band luminosity threshold samples.
Bosch, Frank C. van den   +4 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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