Results 171 to 180 of about 2,783,159 (312)

Lithium Isotopic Analysis of Spodumene by Secondary Ion Mass Spectrometry. [PDF]

Rapid Commun Mass Spectrom
Sharpe R, Fayek M, Luo JC.
europepmc   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Utilization Patterns of Hospital Biobank Samples: Time to First Use and Material-Specific Demand. [PDF]

J Clin Med
Mucher P, Bayer M, Flieder I, Humer GT, Hou L, Koll A, Radakovics A, Ristic N, Schickbauer T, Müller W, Nguyen VL, Kim-Tran M, Szabo A, Hainfellner JA, Hofer P, Perkmann T, Wagner OF, Haslacher H.   +17 more
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Relation Between Thermal Analysis, Phase Composition and Structure of Polyurethane Adhesives for Application in Wooden Structural Joints. [PDF]

Polymers (Basel)
Szumera M, Rutkowski P, Berezicka A, Gajek M, Handke B, Jeleń P, Kwiecień K, Kwiecień A, Śliwa-Wieczorek K.   +8 more
europepmc   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Metabolic balance studies: A comprehensive protocol and methodological approach for assessing intestinal function. [PDF]

Intest Fail
Andersen JHM, Verbiest A, Hvistendahl M, Vanuytsel T, Jeppesen PB.   +4 more
europepmc   +1 more source

Post-Flight Evaluation of Stardust PICA Forebody Heatshield Material

, 2008
This presentation was part of the session : Sample Return ChallengesSixth International Planetary Probe WorkshopPhenolic Impregnated Carbon Ablator (PICA) was developed at NASA Ames Research Center under the lightweight ceramic ablator development ...
Ellerby, Don, Milos, Frank, Stackpoole, Mairead, Lavelle, Joseph, Cozmuta, Ioana, Kontinos, Dean, Arnold, J. O.   +6 more
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

The Development of a Sample Controlled Differential Scanning Calorimeter and its Application to the Study of Different Reaction Types

A new sample controlled DSC (SC-DSC) system has been developed, which for the first time has enabled the benefits of sample controlled thermal analysis to be extended to the widely used technique of DSC.
Rooney, James J.
core