Results 41 to 50 of about 6,116,936 (306)

Optimisation of sample thickness for THz-TDS measurements [PDF]

open access: yes, 2007
How thick should the sample be for a transmission THz-TDS measurement? Should the sample be as thick as possible? The answer is `no'. Although more thickness allows T-rays to interact more with bulk material, SNR rolls off with thickness due to signal ...
Abbott   +26 more
core   +2 more sources

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

open access: yesFEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura   +8 more
wiley   +1 more source

Degradation of the State of a Ball Track at the ZP 6600

open access: yesManagement Systems in Production Engineering, 2017
The article deals with the examination of the state of the ball track of the heavy mining machine ZP6600/Z79. It gives results of material exams which were taken on given samples and describes the progress and results of the numerical computation of the ...
Klouda Petr   +4 more
doaj   +1 more source

A resource of lipidomics and metabolomics data from individuals with undiagnosed diseases

open access: yesScientific Data, 2021
Measurement(s) Metabolomics • Lipidomics Technology Type(s) gas chromatography-mass spectrometry • Ultra High-performance Liquid Chromatography/Tandem Mass Spectrometry Factor Type(s) age group • sex Sample Characteristic - Organism Homo sapiens Sample ...
Jennifer E. Kyle   +10 more
doaj   +1 more source

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

open access: yesFEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker   +9 more
wiley   +1 more source

Review on high-pressure spark plasma sintering and simulation of the impact of die/punch material combinations on the sample temperature homogeneity

open access: yesOpen Ceramics, 2023
This paper provides a thorough review on high-pressure spark plasma sintering (HP-SPS) experiments conducted to date, with a focus on different tooling materials and their impact on microstructural, mechanical and optical properties of the resulting ...
Matěj Nižňanský   +4 more
doaj   +1 more source

Model-Free Data-Driven Methods in Mechanics: Material Data Identification and Solvers [PDF]

open access: yes, 2019
This paper presents an integrated model-free data-driven approach to solid mechanics, allowing to perform numerical simulations on structures on the basis of measures of displacement fields on representative samples, without postulating a specific ...
Leygue, Adrien   +2 more
core   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Investigations on the Material Efficacy of Failed Helical Gears in a Gear Train [PDF]

open access: yes, 2013
An investigation on the material efficacy of failed helical gears in the gearbox of an automobile has been carried out. Two helical gear samples taken as representatives of the whole of six in the gearbox were denoted as samples A and B.
Abidakun, O.A.   +2 more
core  

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

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