Results 71 to 80 of about 22,781,464 (398)
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Possible Indications of Electronic Inhomogeneities in Superconducting Nanowire Detectors
The voltage-carrying state of superconducting NbTiN nanowires, used for single-photon detectors, is analyzed. Upon lowering the current, the wire returns to the superconducting state in a steplike pattern, which differs from sample to sample. Elimination
Driessen, E. F. C.+2 more
core +1 more source
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro+2 more
wiley +1 more source
Sound propagation through bone tissue [PDF]
Effect of perforation on structure borne sound propagation through rigid porous materials has been investigated. Experimental works has been carried out on rigid porous materials with and without perforations.
Aygun, Haydar
core
Deciphering Photographic Papers: Material Insights into 20th-Century Ilford and Kodak Sample Books
Fiber-based black-and-white developing-out papers (DOPs) were among the most widely used photographic supports of the 20th century. Their broad use, structural complexity, and range of surface finishes, alongside evolving manufacturing practices ...
Laura-Cassandra Vălean+3 more
doaj +1 more source
The particle generation of medical implants and drug coated balloons (DCB) is evaluated by simulating the implantation process and collecting the released particle material.
Kurzhals Anja+6 more
doaj +1 more source
Sample storage conditions significantly influence faecal microbiome profiles
Sequencing-based studies of the human faecal microbiota are increasingly common. Appropriate storage of sample material is essential to avoid the introduction of post-collection bias in microbial community composition.
J. Choo, L. Leong, G. Rogers
semanticscholar +1 more source
Evolutionary interplay between viruses and R‐loops
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi+4 more
wiley +1 more source
Comparison of sample materials for S100b analysis
Head injury is a potentially lethal and frequently occurring condition in the emergency department (ED). Reliable and fast diagnosis is important both for patients and flow in the ED. Circulating S100B is used to rule out the need for head computer tomography in low-risk patients with mild head injury.
Kasper Krogh Nielsen+3 more
openaire +2 more sources
Purification tags markedly affect self‐aggregation of CPEB3
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito+6 more
wiley +1 more source