Results 71 to 80 of about 22,781,464 (398)

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Possible Indications of Electronic Inhomogeneities in Superconducting Nanowire Detectors

open access: yes, 2012
The voltage-carrying state of superconducting NbTiN nanowires, used for single-photon detectors, is analyzed. Upon lowering the current, the wire returns to the superconducting state in a steplike pattern, which differs from sample to sample. Elimination
Driessen, E. F. C.   +2 more
core   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Sound propagation through bone tissue [PDF]

open access: yes, 2015
Effect of perforation on structure borne sound propagation through rigid porous materials has been investigated. Experimental works has been carried out on rigid porous materials with and without perforations.
Aygun, Haydar
core  

Deciphering Photographic Papers: Material Insights into 20th-Century Ilford and Kodak Sample Books

open access: yesHeritage
Fiber-based black-and-white developing-out papers (DOPs) were among the most widely used photographic supports of the 20th century. Their broad use, structural complexity, and range of surface finishes, alongside evolving manufacturing practices ...
Laura-Cassandra Vălean   +3 more
doaj   +1 more source

Automatic particle analysis by Raman spectroscopy – evaluation of sample preparation and optimum background material

open access: yesCurrent Directions in Biomedical Engineering, 2017
The particle generation of medical implants and drug coated balloons (DCB) is evaluated by simulating the implantation process and collecting the released particle material.
Kurzhals Anja   +6 more
doaj   +1 more source

Sample storage conditions significantly influence faecal microbiome profiles

open access: yesScientific Reports, 2015
Sequencing-based studies of the human faecal microbiota are increasingly common. Appropriate storage of sample material is essential to avoid the introduction of post-collection bias in microbial community composition.
J. Choo, L. Leong, G. Rogers
semanticscholar   +1 more source

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Comparison of sample materials for S100b analysis

open access: yesScandinavian Journal of Clinical and Laboratory Investigation
Head injury is a potentially lethal and frequently occurring condition in the emergency department (ED). Reliable and fast diagnosis is important both for patients and flow in the ED. Circulating S100B is used to rule out the need for head computer tomography in low-risk patients with mild head injury.
Kasper Krogh Nielsen   +3 more
openaire   +2 more sources

Purification tags markedly affect self‐aggregation of CPEB3

open access: yesFEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy