Results 71 to 80 of about 2,520,256 (267)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
MicroMetal–organic frame (MOF) materials may have the advantages of a regular pore structure, large porosity, and large specific surface area, which could provide better catalytic activity, but they have some disadvantages in electrocatalysis.
Haobo Wang +6 more
doaj +1 more source
Materials Properties: Heterogeneity and Appropriate Sampling Modes
Journal of AOAC INTERNATIONAL, 2015 Abstract The target audience for this Special Section comprises parties related to the food and feed sectors, e.g., field samplers, academic and industrial scientists, laboratory personnel, companies, organizations, regulatory bodies, and agencies who are responsible for sampling, as well as project leaders, project managers, quality ...
openaire +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
International Journal of Digital EarthHigh-quality samples for training and validation are crucial for land cover classification, especially in some complex scenarios. The reliability, representativeness, and generalizability of the sample set are important for further researches.
Yan Wang +5 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Effect of magnetic viscosity on magnetic property measurements of hard magnetic materials
Стандартные образцы, 2018 Purpose. This paper is devoted to investing of the effect of magnetic viscosity on the results of measurements of the main hysteresis characteristics of hard magnetic alloys in an open magnetic circuit of vibrating sample magnetometer.Materials and ...
A. V. Perepelkina +3 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Advances in Sample PreparationThe principle of Fourier Transform Infrared (FTIR) spectroscopy is based on atoms vibration and rotation, and it has become a universal and widely used spectral methodology to detect the internal molecular structures in all kinds of fields.
Yahui Gong, Xuerong Chen, Wei Wu
doaj +1 more source