Results 121 to 130 of about 7,654,949 (307)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Advances in Sample PreparationTetracyclines are widely used antibiotics in animal farming, raising concerns over their residues in food and associated health risks. Current methods for residue determination are complex, time-consuming, and produce substantial solvent waste ...
Anne Oldeide Hay, Frederik André Hansen
doaj +1 more source
Monolithic Materials for Sample Preparation and Separation in Proteome Study
, 2011 Monolithic Materials for Sample Preparation and Separation in Proteome ...
袁辉明, 梁玉, 张玉奎, 张丽华
core
Greenness of extraction procedures involving biochar-based sorbents for organic compounds
In the field of green sample preparation, new challenges are emerging for guaranteeing sustainability of analytical procedures and remarkable efforts have been made to develop materials from natural and/or renewable sources. In such a scenario, biochar
Antonella Profumo +2 more
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Advances in Sample PreparationA rapid, sustainable, and efficient analytical method based on Rotating Disk Sorptive–Dispersive Extraction (RDSDE) coupled to HPLC–DAD was developed and validated for the determination of florfenicol in animal plasma.
Nicolás Morales-Cortínez +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Advances in Sample PreparationFor the first time, polymer microfibers filled in pipette tip format were used to extract polycyclic aromatic hydrocarbons from river water. Centrifugal force was used to push the sample through the sorbent, thereby increasing the speed and throughput of
Ewelina Czyz +5 more
doaj +1 more source
Tracking Microwave-Assisted Sample Preparation Through the Last Years
, 2018 Sample preparation assisted by microwave irradiation has noticeablyincreased over the past decade, reducing the time spent on this step, due toits heating mechanism. The daily laboratory analysis has benefited from the useof microwave-assisted processes,
Claudia E. Domini +9 more
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source