Results 161 to 170 of about 7,654,949 (307)

Fast and Scalable Sample Preparation for Integrated Metabolome and Exposome-Wide Association Studies (MWAS/ExWAS). [PDF]

Anal Chem
Füreder J, Müller A, Guerra G, Sieri S, Feuerstein ML, Warth B.   +5 more
europepmc   +1 more source

Sample Preparation and GC×GC: Fundamental Allies to Unravel MOSH and MOAH Contamination [PDF]

editorial reviewedFood analysis is swiftly evolving, embracing advanced analytical techniques to tackle increasingly complex inquiries. In the realm of analytical chemistry, two overarching trends are discernible.
Purcaro, Giorgia
core  

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Green Analytical Workflows: Recent Advances in Sample Preparation and Instrumental Analysis of Food Contact Materials. [PDF]

Molecules
Cortesi L, Riboni N, Facchini C, Bianchi F.   +3 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Sample Preparation for Imaging-Based Spatial Transcriptomics in Rigid Plant Tissues (Roots, Shoots). [PDF]

Bio Protoc
Liu H, Zhang J, Zhu M.
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

"If the Shoe Fits?"-Benchmarking Plasma Proteomic Sample-Preparation Workflows Across Human and Rat Biofluids. [PDF]

Mol Cell Proteomics
Emery-Corbin SJ, Steele JR, Multari DH, Tanuwidjaya E, Hanchapola I, Sivaraman KK, Lee HC, Blundell SA, Ali I, O'Brien TJ, Faridi P, Schittenhelm RB.   +11 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Optimized tissue sample preparation for cryo-electron tomography using serial lift-out. [PDF]

Biophys Rep
Du W, Yang J, Guo Q.
europepmc   +1 more source