Results 41 to 50 of about 9,899,312 (276)

Optimizing prevalence estimates for a novel pathogen by reducing uncertainty in test characteristics

Epidemics, 2022
Emergence of a novel pathogen drives the urgent need for diagnostic tests that can aid in defining disease prevalence. The limitations associated with rapid development and deployment of these tests result in a dilemma: In efforts to optimize prevalence ...
Daniel B. Larremore, Bailey K. Fosdick, Sam Zhang, Yonatan H. Grad   +3 more
doaj   +1 more source

Sample size Calculation I.

, 2019
Sample size Calculation I.
José Manuel Olivares (6264224), Raimundo Mateos (3706411), Alejandro García Caballero (6264227), María Lado-Codesido (6264218), Cristina Méndez Pérez (6264221)   +4 more
core   +1 more source

Sample size Calculation II.

, 2019
Sample size Calculation II.
José Manuel Olivares (6264224), Raimundo Mateos (3706411), Alejandro García Caballero (6264227), María Lado-Codesido (6264218), Cristina Méndez Pérez (6264221)   +4 more
core   +1 more source

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Study Design, Errors and Sample Size Calculation in Medical Research

Airway, 2020
The choice of an appropriate study design is one of the crucial steps in the research process after framing a research question. A single research question may fit into different study designs.
Sabyasachi Das, Pradeep A Dongare, Umesh Goneppanavar, Rakesh Garg, S Bala Bhaskar   +4 more
doaj   +1 more source

Sample size calculations for skewed distributions [PDF]

BMC Medical Research Methodology, 2015
Sample size calculations should correspond to the intended method of analysis. Nevertheless, for non-normal distributions, they are often done on the basis of normal approximations, even when the data are to be analysed using generalized linear models (GLMs).For the case of comparison of two means, we use GLM theory to derive sample size formulae, with
Cundill, B, Alexander, NDE
openaire   +4 more sources

At what sample size do correlations stabilize? [PDF]

, 2013
Sample correlations converge to the population value with increasing sample size, but the estimates are often inaccurate in small samples. In this report we use Monte-Carlo simulations to determine the critical sample size from which on the magnitude of ...
Perugini, Marco, Schönbrodt, Felix D.
core   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

Considerations when calculating the sample size for an inequality test [PDF]

Korean Journal of Anesthesiology, 2016
Click here for Korean Translation.Calculating the sample size is a vital step during the planning of a study in order to ensure the desired power for detecting clinically meaningful differences.
Junyong In
doaj   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source