Results 81 to 90 of about 9,899,312 (276)

The Impact of Tenapanor on Body Composition and Blood Pressure in Peritoneal Dialysis Patients: A Pilot Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Instruction Tenapanor potentially affects fluid volume and blood pressure. This study explored its effects on these parameters in patients undergoing peritoneal dialysis (PD). Methods We conducted a single‐arm, prospective observational study that enrolled 10 patients on PD with hyperphosphatemia who were newly initiated on tenapanor.
Shun Yoshida   +11 more
wiley   +1 more source

Comparing two Formulas of Sample Size Determination for Prevalence Studies

open access: yesعلوم بهداشتی ایران, 2013
Background and purpose: Sample size and its determination is one of the most important problems in health researches. Calculating sample size for prevalence studies is one of the common questions of sample size topics.
Hamed Tabesh   +2 more
doaj  

Power analysis, sample size calculation for testing the largest binomial probability

open access: yesStatistical Theory and Related Fields, 2020
A procedure is developed for power analysis and sample size calculation for a class of complex testing problems regarding the largest binomial probability under a combination of treatments.
Thuan Nguyen, Jiming Jiang
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Sample Size Calculation and Power Analysis for the General Mediation Analysis Method

open access: yesStats
Mediation analysis is a widely used statistical technique for identifying the mechanisms underlying the relationship between an exposure and an outcome. However, accurate power analysis and sample size determination for mediation models that involve non ...
Nubaira Rizvi   +3 more
doaj   +1 more source

Do Registered Reports Improve Sample Size Planning in Psychology? An exploratory study [PDF]

open access: yes, 2022
openThe paper aims to investigate whether Registered Reports (RRs) published on OSF used a justified sample size.The paper aims to investigate whether Registered Reports (RRs) published on OSF used a justified sample ...
NORSA, REBECCA
core  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Sample size calculation : proportions [PDF]

open access: yes, 2011
Um problema bastante comum, cuja definição é fundamental na etapa de criação de um projeto de pesquisa é o cálculo do tamanho da amostra. A partir deste cálculo, será definido o cronograma de coleta de dados, ou mesmo a viabilidade do projeto. O objetivo
Hirakata, Vania Naomi   +1 more
core   +1 more source

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