Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Some Practical Guidelines for Effective Sample-Size Determination in Observational Studies
The purpose of this present study was to determine the right sample size in observational study which is focusing on medical or health sciences field. Sample size calculation is actually depends on the type of how the study is designed.
Wan Muhamad Amir W Ahmad +3 more
doaj
Two-stage versus sequential sample-size determination in regression analysis of simulation experiments [PDF]
Regression Analysis;Experimental Design;Simulation Models ...
Groenendaal, W.J.H. van +1 more
core +1 more source
Faktor-Faktor Yang Mempengaruhi Penetapan Audit Fees (Studi Empiris Perusahaan Manufaktur yang Terdaftar di Bursa Efek Indonesia Periode 2014-2016) [PDF]
This research was conducted to examine the factors that may affect the determination of the external audit fees on companies listed in Indonesia Stock Exchange (IDX).
, Dra. Nursiam, M.H., Ak., CA +1 more
core
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
The Tip of the Red Giant Branch and Distance of the Magellanic Clouds: results from the DENIS survey [PDF]
We present a precise determination of the apparent magnitude of the tip of the red giant branch (TRGB) in the I (0.8 micron), J (1.25 micron), and K_S (2.15 micron) bands from the luminosity function of a sample of data extracted from the DENIS catalogue
Cioni, Maria-Rosa. L. +3 more
core +2 more sources
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
The Understanding on How to Determine Sample Size in Psychological Science: Data and Simulation
The lack of knowledge on how to determine sample sizes in experiments is arguably one of the main reasons underlying the replication crisis in psychological science. A survey distributed among Indonesian students and researchers concerning 1) familiarity
Wisnu Wiradhany +3 more
doaj +1 more source
Impact of small sample sizes on the internal quality control: statistical uncertainties in the determination of root mean square deviations with respect to the sample mean (RMSD) or to a target value (RMSTD) [PDF]
Christian Beier
openalex +1 more source

