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Dose and sample size determination for multi-drug combination studies [PDF]
, 2009 Preclinical experiment on multi-drug combination has an increasingly important role in (especially cancer) drug development because of the need to reduce development time and costs.
Fang, HB, Tan, MT, Tian, GL
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Bayesian sample size determination for cost-effectiveness studies with censored data. [PDF]
PLoS ONE, 2018 Cost-effectiveness models are commonly utilized to determine the combined clinical and economic impact of one treatment compared to another. However, most methods for sample size determination of cost-effectiveness studies assume fully observed costs and
Daniel P Beavers, James D Stamey
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Sample size determination for clinical research [PDF]
Muscle Ligaments and Tendons Journal, 2019 Calculating the sample size is a most important determinant of statistical power of a study. A study with inadequate power, unless being conducted as a safety and feasibility study, is unethical. However, sample size calculation is not an exact science, and therefore it is important to make realistic and well researched assumptions before choosing an ...
Wang D +3 more
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Adaptive sample size determination for the development of clinical prediction models
Diagnostic and Prognostic Research, 2021 Background We suggest an adaptive sample size calculation method for developing clinical prediction models, in which model performance is monitored sequentially as new data comes in.
Evangelia Christodoulou +6 more
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Acceptance sampling plan for multiple manufacturing lines using EWMA process capability index [PDF]
, 2017 The problem of developing a product acceptance determination procedure for multiple characteristics has attracted the quality assurance practitioners. Due to sufficient demands of consumers, it may not be possible to deliver the quantity ordered on time ...
Arif, O.H., Aslam, M., Jun, C.-H.
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Proteomes, 2021 Specific plasma proteins serve as valuable markers for various diseases and are in many cases routinely measured in clinical laboratories by fully automated systems.
Lou-Ann C. Andersen +5 more
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Determination of regional bone blood flow by means of fluorescent microspheres using an automated sample-processing procedure [PDF]
, 2003 The determination of regional blood flow utilizing fluorescent microspheres (FMs) is an established method for numerous organs. Recent progress, in particular the automation of sample processing, has further improved this method.
Anetzberger, H. +3 more
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Sample size determination for mediation analysis of longitudinal data
BMC Medical Research Methodology, 2018 Background Sample size planning for longitudinal data is crucial when designing mediation studies because sufficient statistical power is not only required in grant applications and peer-reviewed publications, but is essential to reliable research ...
Haitao Pan +3 more
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Sample size determination in combinatorial chemistry. [PDF]
Proceedings of the National Academy of Sciences, 1995 Combinatorial chemistry is gaining wide appeal as a technique for generating molecular diversity. Among the many combinatorial protocols, the split/recombine method is quite popular and particularly efficient at generating large libraries of compounds.
Kevin T. Chapman +4 more
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Determination of the optimal sample size for a clinical trial accounting for the population size [PDF]
, 2017 The problem of choosing a sample size for a clinical trial is a very common one. In some settings, such as rare diseases or other small populations, the large sample sizes usually associated with the standard frequentist approach may be infeasible ...
Anscombe +19 more
core +2 more sources