Results 61 to 70 of about 2,253,933 (319)

Preoperative Cytopenia in Patients Affected by High‐Risk Neuroblastoma: Just a Matter of Platelets?

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims In patients affected by high‐risk neuroblastoma (HR‐NB), complete macroscopic resection (CMR) is associated with better outcomes. These patients are often cytopenic due to intensive induction regimens. The aim of the present study is to assess the impact of preoperative cytopenia on surgical outcome in patients with HR‐NB ...
Giorgio Persano   +13 more
wiley   +1 more source

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed   +5 more
wiley   +1 more source

Nested Maximum Entropy Designs for Computer Experiments

open access: yesMathematics, 2023
Presently, computer experiments with multiple levels of accuracy are widely applied in science and engineering. This paper introduces a class of nested maximum entropy designs for such computer experiments.
Weiyan Mu, Chengxin Liu, Shifeng Xiong
doaj   +1 more source

Optimal sample size determination in adaptive seamless phase II/III design [PDF]

open access: yes, 2016
The adaptive seamless phase II/III design combines the conventional separate phases II and III trials into a single trial, and it allows for adaptations (e.g. sample size reassessment and early stopping for futility or success) after the interim analysis.
Xu, Zhongying
core  

Laser Spectroscopic Measurement of Helium Isotope Ratios

open access: yes, 2003
A sensitive laser spectroscopic method has been applied to the quantitative determination of the isotope ratio of helium at the level of 3He/4He = 10^-7 - 10^-5.
Bjoklund   +24 more
core   +1 more source

The X-ray Luminosity Function of Nearby Rich and Poor Clusters of Galaxies: A Cosmological Probe [PDF]

open access: yes, 1999
In this letter, we present a new determination of the local (z10^43 ergs/sec. We combine our data with previous work in order to explore possible constraints imposed by the shape of the XLF on cosmological models. A set of currently viable cosmologies is
Briel U. G.   +12 more
core   +3 more sources

Parent‐to‐Child Information Disclosure in Pediatric Oncology

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite professional consensus regarding the importance of open communication with pediatric cancer patients about their disease, actual practice patterns of disclosure are understudied. Extant literature suggests a significant proportion of children are not told about their diagnosis/prognosis, which is purported to negatively ...
Rachel A. Kentor   +12 more
wiley   +1 more source

Prolonged Corrected QT Interval as an Early Electrocardiographic Marker of Cyclophosphamide‐Induced Cardiotoxicity in Pediatric Hematology and Oncology Patients

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura   +5 more
wiley   +1 more source

Equivalence Test and Sample Size Determination Based on Odds Ratio in an AB/BA Crossover Study with Binary Outcomes

open access: yesAxioms
Crossover trials are specifically designed to evaluate treatment effects within individual participants through within-subject comparisons. In a standard AB/BA crossover trial, participants are randomly allocated to one of two treatment sequences: either
Shi-Fang Qiu, Xue-Qin Yu, Wai-Yin Poon
doaj   +1 more source

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