Results 151 to 160 of about 1,365,928 (295)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Design of Variables Sampling Plan in Agro-Allied Industry for Packed Yam Flour in-view of International Regulatory Standards

Journal of Applied Sciences and Environmental Management
To stay competitive in today’s global market, manufacturers must ensure products released to consumers, meet international regulations and standards and this can only be done by putting in place sampling plans to guarantee the release of quality lots of ...
K. Ezewu, E. C. Enujeke, M. E. Amagre
doaj  

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Sampling plan of SB Brasil 2023: precision of dmft and DMFT estimates for the study domains. [PDF]

Braz Oral Res
Alves MCGP, Alencar GP, Vargas AMD, Ferreira RC, Bernal RTI.   +4 more
europepmc   +1 more source

ADAPTIVE SAMPLING PLAN DESIGN METODOLOGY FOR REVERSE ENGINEERING ACQUISITION [PDF]

, 2008
A Courtial, A Weekenmann, B Bidanda, B Sarkar, CK Chua, CM Cheah, CM Cheah, E. Vezzetti, K Kase, KD Creehan, M Cho, M Mortenson, M Sarfraz, N Amenta, PG Ciarlet, R Hoffman, T Varady, X Li   +17 more
core   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Bayesian double group sampling plan for assessing the average number of nonconforming products in manufacturing: a Poisson-Gamma distribution approach. [PDF]

Sci Rep
Hafeez W, Wu S, Aziz N, Abbas Z, Imran M.   +4 more
europepmc   +1 more source

Designing a multiple dependent state sampling plan based on the coefficient of variation. [PDF]

Springerplus, 2016
Yan A, Liu S, Dong X.
europepmc   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source