Results 191 to 200 of about 887,103 (337)

Modeling aperiodic sampling to increase the signal processing bandwidth of the sampling analog optical path

, 2023
Daniil S. Zemtsov, Rostislav S. Starikov
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Experimental analysis of time difference of arrival estimates based on inexactly reconstructed signals. [PDF]

Sci Rep
Wang S, Huang C, Xiang Y, Gao Y, Zhao X, Hua Y.   +5 more
europepmc   +1 more source

Sampling-based Bayesian approaches reveal the importance of quasi-bistable behavior in cellular decision processes on the example of the MAPK signaling pathway in PC-12 cell lines [PDF]

, 2017
Antje Jensch, Caterina Thomaseth, Nicole Radde   +2 more
openalex   +1 more source

Echo cancellation using sampled analog signal processing. [PDF]

, 2018
openaire   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

FZC-TDE: The Algorithm for Real-Time Ultrasonic Stress Measurement at Low Sampling Rates. [PDF]

Micromachines (Basel)
Qiu F, Chen B, Luo C, Chen J, He Z, Zhao J, Gou G.   +6 more
europepmc   +1 more source

MODELING SIGNAL-NOISE PROCESSES SUPPORTS STUDENT CONSTRUCTION OF A HIERARCHICAL IMAGE OF SAMPLE

, 2017
Richard Lehrer
openalex   +2 more sources

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Robust Motor Imagery-Brain-Computer Interface Classification in Signal Degradation: A Multi-Window Ensemble Approach. [PDF]

Biomimetics (Basel)
Lee DG, Lee SB.
europepmc   +1 more source