Results 101 to 110 of about 526,216 (298)
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Application of Jane Jacobs’ Theory in the Analysis of the Borders of Territory Monitoring in Urban Spaces from Citizens’ Points of View in Bandar Abbas [PDF]
This research explored the social and cultural dimensions of monitoring urban spaces with a particular focus on the mental approaches and behavioral patterns of citizens in Bandar Abbas, Iran. Upon utilizing a descriptive and analytical methodology, data
Amirhamzeh Shahbazi +2 more
doaj +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Sociological Analysis of the Relationship between Spirituality, Self-Concept and Type of Clothing [PDF]
In various contexts, the scope and boundaries of coverage are influenced by multiple factors at both micro and macro levels of society. Therefore, this study adopts a novel approach to examining the type of coverage for female students, focusing on the ...
Shahrokh Eftekhari, Halime Enayat
doaj +1 more source
The role of trust in e-government adoption: A systematic literature review [PDF]
Electronic government (e-government) is a concept that has been adopted in most countries for the purposes of providing government services digitally, improving transparency between government and citizens and enabling additional communication channels
Mahmood, M, Osmani, M, Sivarajah, U
core +1 more source
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Increasing suicide rates among Latino/x men in the United States, particularly in Massachusetts, underscore the critical need for culturally responsive suicide prevention interventions.
Airín D. Martínez +8 more
doaj +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Minimum variance stratification of a finite population
This paper considers the combined problem of allocation and stratification in order to minimise the variance of the expansion estimator of a total, taking into account that the population is finite.
Hedlin, Dan
core

