Results 101 to 110 of about 525,400 (298)

Sociological Analysis of the Relationship between Spirituality, Self-Concept and Type of Clothing [PDF]

open access: yesمطالعات اجتماعی روان‌شناختی زنان
In various contexts, the scope and boundaries of coverage are influenced by multiple factors at both micro and macro levels of society. Therefore, this study adopts a novel approach to examining the type of coverage for female students, focusing on the ...
Shahrokh Eftekhari, Halime Enayat
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Sample Size Determination to Evaluate the Impact of Highway Improvements [PDF]

open access: yes, 1989
This paper was prepared for the Department of Transport, as a support document to a main report on the feasibility of measuring responses to highway improvements.
Fowkes, A.S., Watson, S.M.
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

European Survey Data on Attitudes to Equality and Human Rights Technical Paper. Research Series [PDF]

open access: yes, 2019
This report maps the data available on attitudes to equality and human rights issues in Ireland collected in European surveys over the period 2000 to 2018. These surveys provide a rich source of evidence for researchers and policymakers in Ireland.
Fahey, Éamonn   +3 more
core  

Culturally Modifying MassMen for Massachusetts Latino/x Men: Formative Research for the CDC-Funded Massachusetts Comprehensive Suicide Prevention Program

open access: yesAmerican Journal of Men's Health
Increasing suicide rates among Latino/x men in the United States, particularly in Massachusetts, underscore the critical need for culturally responsive suicide prevention interventions.
Airín D. Martínez   +8 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Integration of survey data and big observational data for finite population inference using mass imputation [PDF]

open access: yes, 2018
Multiple data sources are becoming increasingly available for statistical analyses in the era of big data. As an important example in finite-population inference, we consider an imputation approach to combining a probability sample with big observational
Kim, Jae Kwang   +2 more
core   +3 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

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