Results 151 to 160 of about 60,632 (306)

Qualitative research - Part 1. [PDF]

Perspect Clin Res
Ranganathan P, Graetz DE, Hanebrink J, Mathew A, Ravindran V, Pramesh CS.   +5 more
europepmc   +1 more source

Thompson sampling based Monte-Carlo planning in POMDPs

Monte-Carlo tree search (MCTS) has been drawinggreat interest in recent years for planning under uncertainty. One of the key challenges is the tradeoffbetween exploration and exploitation. To addressthis, we introduce a novel online planning algorithmfor
Wu, Feng, Bai, Aijun, Chen, Xiaoping, Zhang, Zongzhang   +3 more
core  

GMM estimation for nonignorable missing data: theory and practice [PDF]

This thesis develops several Generalized Method ofMoments (GMM) estimators for analysing Not Missing at Random (NMAR) data, which is commonly referred to as the self-selection problem in an economic context.
Hemvanich, Sanha
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Real-Time Type 1 Diabetes Self-Management Decision-Making in Adolescents: Protocol for a Longitudinal Mixed Methods Study Using Text Messaging and Continuous Glucose Monitoring. [PDF]

JMIR Res Protoc
DeJonckheere M, Chuisano SA, Lucien J, Amjad F, Duvvuri O, Khan H, Khan M, Mirza R, Ollivierre MJ, Guetterman T, Lin YK, Buis LR, Aikens JE, Richardson C, Lee JM.   +14 more
europepmc   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

A four-phase framework for culturally responsive vaccine messaging. [PDF]

Health Psychol Behav Med
Hamilton K, Balla J, Arroyo AC, Bámaca MY, Epperson AE, Manzo RD, Peña M, Hagger MS.   +7 more
europepmc   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

One Assay to Rule Them All: Development of a Global Environmental DNA Tool to Support Range-Wide Surveys of an Imperiled Sawfish and Its Application in the Eastern Tropical Pacific. [PDF]

Ecol Evol
Cubillos-M JC, Fearing A, Chapman DD, Kyne PM, Dias PJ, Gonzalez C, Lehman RN, Chichaco Y, Huerta-Beltrán BL, McCulloch KL, Toepfer SM, Carlson JK, Phillips NM.   +12 more
europepmc   +1 more source

Finite population properties of predictors based on spatial patterns

When statistical inference is used for spatial prediction, the model-based framework known as kriging is commonly used. The predictor for an unsampled element of a population is a weighted combination of sampled values, in which weights are obtained by ...
Alessandro Vagheggini, Francesca Bruno, Daniela Cocchi   +2 more
core